The 20 Best Major Depression Doctors Near Me in Spartanburg, SC

Find the Top Major Depression Experts and Specialists

Last Updated: 09/19/2026

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MediFind found 320 doctor with experience in Major Depression near Spartanburg, SC. Of these, 232 are Experienced, 69 are Advanced, 16 are Distinguished and 2 are Elite.

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320 providers found
    Advanced in Major Depression
    Advanced in Major Depression
    Referral may be required

    MUSC Health Institute Of Psychiatry

    67 President Street, 67 President Street, 
    Charleston, SC 
    843-792-9888
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Edward Short is a Psychiatrist practicing medicine in Charleston, South Carolina. Dr. Short is rated as an Advanced provider by MediFind in the treatment of Major Depression. He is also highly rated in 4 other conditions, according to our data. His clinical expertise encompasses Bipolar Disorder (BPD), Seasonal Affective Disorder (SAD), Major Depression, Schizoaffective Disorder, and Deep Brain Stimulation. Dr. Short is currently accepting new patients.

    Experienced in Major Depression
    Experienced in Major Depression
    Referral may be required

    Prisma Health Center For Psychiatry

    109 Physicians Drive, Suite B, 
    Greer, SC 
    864-455-8988
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Belynda Veser is a Psychiatrist practicing medicine in Greer, South Carolina. Dr. Veser is rated as an Experienced provider by MediFind in the treatment of Major Depression. She is also highly rated in 1 other condition, according to our data. Her clinical expertise encompasses Alzheimer's Disease, Major Depression, Bipolar Disorder (BPD), and Seasonal Affective Disorder (SAD). Dr. Veser is currently accepting new patients.

    Experienced in Major Depression
    Experienced in Major Depression
    Referral may be required

    MUSC Health Institute Of Psychiatry

    67 President Street, 67 President Street, 
    Charleston, SC 
    843-792-9888
    Languages Spoken:
    English, French
    See accepted insurances
    Accepting New Patients

    Mark George is a Psychiatrist practicing medicine in Charleston, South Carolina. Dr. George is rated as an Experienced provider by MediFind in the treatment of Major Depression. He is also highly rated in 1 other condition, according to our data. His clinical expertise encompasses Schizoaffective Disorder, Seasonal Affective Disorder (SAD), Major Depression, and Bipolar Disorder (BPD). Dr. George is currently accepting new patients.

    Learn about our expert tiers
    Experienced in Major Depression
    Experienced in Major Depression
    Referral may be required

    Prisma Health Psychiatry – Greer OBGYN

    325 Medical Parkway, Suite 100, 
    Greer, SC 
    864-797-9200
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Jessica Obeysekare is a Psychiatrist practicing medicine in Greer, South Carolina. Dr. Obeysekare is rated as an Experienced provider by MediFind in the treatment of Major Depression. Her clinical expertise encompasses Postpartum Depression, Obsessive-Compulsive Disorder (OCD), Seasonal Affective Disorder (SAD), and Generalized Anxiety Disorder (GAD). Dr. Obeysekare is board certified in American Board Of Psychiatry And Neurology. Dr. Obeysekare is currently accepting new patients.

    Experienced in Major Depression

    Dr. Frank A. Peters-Iv
    Psychiatry | Child and Adolescent Psychiatry
    Experienced in Major Depression

    Dr. Frank A. Peters-Iv
    Psychiatry | Child and Adolescent Psychiatry
    Referral may be required

    Prisma Health Behavioral Health–Taylor St.

    1301 Taylor Street, Suite 6J, 
    Columbia, SC 
    803-434-4300
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Frank Peters-Iv is a Psychiatrist and a Child and Adolescent Psychiatrist practicing medicine in Columbia, South Carolina. Dr. Peters-Iv is rated as an Experienced provider by MediFind in the treatment of Major Depression. His clinical expertise encompasses Post-Traumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD), Major Depression, and Seasonal Affective Disorder (SAD). Dr. Peters-Iv is board certified in American Board Of Psychiatry And Neurology. Dr. Peters-Iv is currently accepting new patients.

    Experienced in Major Depression

    Dr. Casey L. Berson
    Psychiatry | Child and Adolescent Psychiatry
    Experienced in Major Depression

    Dr. Casey L. Berson
    Psychiatry | Child and Adolescent Psychiatry
    Referral may be required

    Prisma Health Child Psychiatry And Psychotherapy – Greenville

    10 Patewood Drive, Suite 150, 
    Greenville, SC 
    864-454-5612
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Casey Berson is a Psychiatrist and a Child and Adolescent Psychiatrist practicing medicine in Greenville, South Carolina. Dr. Berson is rated as an Experienced provider by MediFind in the treatment of Major Depression. Her clinical expertise encompasses Oppositional Defiant Disorder (ODD), Post-Traumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD), and Attention Deficit Hyperactivity Disorder (ADHD). Dr. Berson is board certified in American Board Of Psychiatry And Neurology. Dr. Berson is currently accepting new patients.

    Experienced in Major Depression

    Dr. Michael A. Sierra
    Psychiatry | Child and Adolescent Psychiatry
    Experienced in Major Depression

    Dr. Michael A. Sierra
    Psychiatry | Child and Adolescent Psychiatry
    Referral may be required

    Prisma Health Psychiatry And Behavioral Medicine – Greenville

    701 Grove Road, 
    Greenville, SC 
    864-455-8988
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Michael Sierra is a Psychiatrist and a Child and Adolescent Psychiatrist practicing medicine in Greenville, South Carolina. Dr. Sierra is rated as an Experienced provider by MediFind in the treatment of Major Depression. His clinical expertise encompasses Oppositional Defiant Disorder (ODD), Generalized Anxiety Disorder (GAD), Major Depression, and Seasonal Affective Disorder (SAD). Dr. Sierra is board certified in American Board Of Psychiatry And Neurology. Dr. Sierra is currently accepting new patients.

    Sara A. Mccracken, NP
    Nurse Practitioner

    Sara A. Mccracken, NP
    Nurse Practitioner
    Referral may be required

    Telewellness Solutions

    1675 US-17 ALT, 
    Summerville, SC 
    843-415-6753
    Experience:
    14+ years
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Hi, I'm Sara McCracken, a dedicated Family Nurse Practitioner with a passion for providing compassionate, patient-centered care. With over six years in the medical field, I specialize in telehealth, mental health, and weight loss management. I am board-certified by the AANP and committed to delivering evidence-based treatment that supports the unique needs of each patient.My expertise spans psychiatric care, weight loss, and overall wellness. I help individuals manage conditions such as anxiety, depression, and insomnia while also guiding them toward sustainable weight loss and better overall health. Currently, I provide telehealth services across multiple states, including South Carolina, Arizona, and Ohio, ensuring accessible and convenient care.I hold a Master of Science in Nursing from South University and a Bachelor's from the University of South Carolina. My approach to care is rooted in empathy, open communication, and collaboration. I believe that healthcare should be personalized, ensuring that patients feel heard, understood, and supported. Whether through mental health support or wellness coaching, I’m here to guide my patients toward a healthier and happier life. Mccracken, NP is rated as undefined provider by MediFind in the treatment of Major Depression. Her clinical expertise encompasses Major Depression, Generalized Anxiety Disorder (GAD), Bipolar Disorder (BPD), and Post-Traumatic Stress Disorder (PTSD). Mccracken, NP is currently accepting new patients.

    Distinguished in Major Depression

    Dr. Timothy D. Malone
    Psychiatry | Child and Adolescent Psychiatry
    Distinguished in Major Depression

    Dr. Timothy D. Malone
    Psychiatry | Child and Adolescent Psychiatry
    Referral may be required

    Three Rivers Behavioral Health LLC

    2900 Sunset Blvd, 
    West Columbia, SC 
    803-796-9911
    Languages Spoken:
    English
    See accepted insurances
    Offers Telehealth

    Timothy Malone is a Psychiatrist and a Child and Adolescent Psychiatrist practicing medicine in West Columbia, South Carolina. Dr. Malone is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 6 other conditions, according to our data. His clinical expertise encompasses Major Depression, Seasonal Affective Disorder (SAD), Schizophrenia, and Post-Traumatic Stress Disorder (PTSD). Dr. Malone is board certified in American Board Of Psychiatry And Neurology.

    Experienced in Major Depression
    Experienced in Major Depression
    Referral may be required

    Clemson University-Redfern Health Center

    735 McMillan Rd, 
    Clemson, SC 
    864-656-2233
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients

    Christopher Pelic is a Psychiatrist practicing medicine in Clemson, South Carolina. Dr. Pelic is rated as an Experienced provider by MediFind in the treatment of Major Depression. His clinical expertise encompasses Seasonal Affective Disorder (SAD), Major Depression, Obsessive-Compulsive Disorder (OCD), and Generalized Anxiety Disorder (GAD). Dr. Pelic is currently accepting new patients.

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    Upstate Psychiatry PA

    27 Memorial Medical Dr, 
    Greenville, SC 
    864-295-2221
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Jeanne Morrow is a Psychiatrist practicing medicine in Greenville, South Carolina. Dr. Morrow is rated as a Distinguished provider by MediFind in the treatment of Major Depression. She is also highly rated in 6 other conditions, according to our data. Her clinical expertise encompasses Seasonal Affective Disorder (SAD), Major Depression, Generalized Anxiety Disorder (GAD), and Bipolar Disorder (BPD). Dr. Morrow is currently accepting new patients.

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    Mofdaps Comp Behav Health Specs

    1203 48th Ave N Ste 202, 
    Myrtle Beach, SC 
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Adedapo Oduwole is a Psychiatrist practicing medicine in Myrtle Beach, South Carolina. Dr. Oduwole is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 9 other conditions, according to our data. His clinical expertise encompasses Seasonal Affective Disorder (SAD), Major Depression, Bipolar Disorder (BPD), and Schizoaffective Disorder. Dr. Oduwole is currently accepting new patients.

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    Carolina Psychiatric Services Inc

    160 Medical Cir, 
    West Columbia, SC 
    803-796-6811
    Languages Spoken:
    English
    See accepted insurances
    Offers Telehealth

    Robert Ornelas is a Psychiatrist practicing medicine in West Columbia, South Carolina. Dr. Ornelas is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 4 other conditions, according to our data. His clinical expertise encompasses Seasonal Affective Disorder (SAD), Major Depression, Generalized Anxiety Disorder (GAD), and Bipolar Disorder (BPD).

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    MUSC Health Kershaw Medical Center

    1315 Roberts St, 
    Camden, SC 
    803-432-4311
    Languages Spoken:
    English, Hindi, Kannada, Spanish, Telugu
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Shankar Yalamanchili is a Psychiatrist practicing medicine in Camden, South Carolina. Dr. Yalamanchili is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 10 other conditions, according to our data. His clinical expertise encompasses Alzheimer's Disease, Major Depression, Vascular Dementia, and Seasonal Affective Disorder (SAD). Dr. Yalamanchili is currently accepting new patients.

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    Piedmont Psychiatric Service PA

    2094 Woodruff Rd, 
    Greenville, SC 
    864-676-9211
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Jeffrey Smith is a Psychiatrist practicing medicine in Greenville, South Carolina. Dr. Smith is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 4 other conditions, according to our data. His clinical expertise encompasses Bipolar Disorder (BPD), Major Depression, Seasonal Affective Disorder (SAD), and Generalized Anxiety Disorder (GAD). Dr. Smith is currently accepting new patients.

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    The Charles Lea Center Inc.

    195 Burdette St, 
    Spartanburg, SC 
    864-585-0322
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients

    Richard Thompson is a Psychiatrist practicing medicine in Spartanburg, South Carolina. Dr. Thompson is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 8 other conditions, according to our data. His clinical expertise encompasses Major Depression, Generalized Anxiety Disorder (GAD), Seasonal Affective Disorder (SAD), and Obsessive-Compulsive Disorder (OCD). Dr. Thompson is currently accepting new patients.

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    Office

    1483 Tobias Gadson Blvd Ste 107, 
    Charleston, SC 
    888-852-6672
    Languages Spoken:
    English, Castilian, Spanish
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Eduardo Cifuentes is a Psychiatrist practicing medicine in Charleston, South Carolina. Dr. Cifuentes is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 8 other conditions, according to our data. His clinical expertise encompasses Major Depression, Seasonal Affective Disorder (SAD), Bipolar Disorder (BPD), and Schizoaffective Disorder. Dr. Cifuentes is currently accepting new patients.

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    Upstate Psychiatry PA

    27 Memorial Medical Dr, 
    Greenville, SC 
    864-295-2221
    Languages Spoken:
    English
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Barnwell Myers-Iii is a Psychiatrist practicing medicine in Greenville, South Carolina. Dr. Myers-Iii is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 6 other conditions, according to our data. His clinical expertise encompasses Bipolar Disorder (BPD), Seasonal Affective Disorder (SAD), Major Depression, and Generalized Anxiety Disorder (GAD). Dr. Myers-Iii is currently accepting new patients.

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    Office

    2777 Speissegger Dr, 
    North Charleston, SC 
    843-747-5830
    Languages Spoken:
    English, Castilian, Spanish
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Steven Lopez is a Psychiatrist practicing medicine in North Charleston, South Carolina. Dr. Lopez is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 5 other conditions, according to our data. His clinical expertise encompasses Seasonal Affective Disorder (SAD), Schizoaffective Disorder, Major Depression, and Bipolar Disorder (BPD). Dr. Lopez is currently accepting new patients.

    Distinguished in Major Depression
    Distinguished in Major Depression
    Referral may be required

    Upstate Psychiatry PA

    27 Memorial Medical Dr, 
    Greenville, SC 
    864-295-2221
    Languages Spoken:
    English, Castilian, Spanish
    See accepted insurances
    Accepting New Patients
    Offers Telehealth

    Mario Galvarino is a Psychiatrist practicing medicine in Greenville, South Carolina. Dr. Galvarino is rated as a Distinguished provider by MediFind in the treatment of Major Depression. He is also highly rated in 6 other conditions, according to our data. His clinical expertise encompasses Bipolar Disorder (BPD), Seasonal Affective Disorder (SAD), Major Depression, and Generalized Anxiety Disorder (GAD). Dr. Galvarino is currently accepting new patients.

    Showing 1-20 of 320

    Last Updated: 09/19/2026

    What is the definition of Major Depression?

    Depression is feeling sad, blue, unhappy, or down in the dumps. Most people feel this way once in a while.

    Major depression is a mood disorder. It occurs when feelings of sadness, loss, anger, or frustration get in the way of your life over a long period of time. It also changes how your body works.

    What are the different types of depression? 

    It’s normal to feel depressed or experience moments of sadness sometimes. But when someone is diagnosed with major depression, it means they’ve been experiencing very strong and long-lasting feelings of sadness for most of the day, nearly every day, for at least two weeks.  

    Other types of depression and conditions that can have similar symptoms include: 

    • Bipolar disorder includes periods of depression and periods of very high energy and mood (mania) 
    • Persistent depressive disorder (dysthymia) is long-lasting depression with less severe symptoms than major depressive disorder 
    • Psychotic depression is depression with severe symptoms like seeing or hearing things that aren’t there (hallucinations) or believing things that aren’t true (delusions) 

    What kind of doctor is best for major depression? 

    Psychiatrists are medical doctors who specialize in mental health and can prescribe medications. Other helpful professionals include psychologists, therapists, and counselors who provide talk therapy to help people manage their feelings.  

    What are the symptoms of major depression? 

    Symptoms of major depression can vary from person to person, range from mild to severe, and last from a short period to a very long time. This includes:  

    • Feeling very sad, anxious, or empty all the time 
    • Feeling hopeless or negative about the future 
    • Being easily irritated or frustrated 
    • Feeling guilty or worthless 
    • Losing interest in activities once enjoyed 
    • Feeling very tired and having no energy 
    • Having trouble concentrating or making decisions 
    • Having trouble sleeping or sleeping too much 

    Can a person recover from major depression? 

    Major depression is one of the most common and most treatable mental health conditions. However, it doesn’t always feel this way to the person experiencing symptoms. It’s normal to have feelings of helplessness, hopelessness, or worthlessness when depressed. Fortunately, people with major depression can find relief from symptoms with the right treatment plan. This can include medications, therapy, or a combination of both.   

    Is major depression a disability? 

    The Americans with Disability Act (ADA) recognizes major depression as a disability, although not everyone living with the condition qualifies for disability protection. Depression is considered a disability when it affects a person’s ability to work, go to school, interact with others, and do everyday activities.   

    How do I support someone with major depression? 

    You can support someone with major depression by: 

    • Encouraging them to seek help from a doctor or therapist 
    • Listening to them and showing that you care 
    • Being patient and understanding 
    • Helping them with daily tasks if they need it 
    • Encouraging them to stay active and do things they enjoy 

    When should I see a Major Depression doctor near Spartanburg, SC?

    There are various reasons why you may want to see a specialist, such as: 

    • Your primary care provider recommends it. 
    • Your condition requires expert knowledge and specialized care. 
    • Your symptoms persist or worsen despite treatment. 
    • You need specialized testing or procedures. 
    • You want a second opinion.  

    What should I consider when choosing a Major Depression doctor near Spartanburg, SC?

    It’s important to see a provider with expertise in your specific condition. Each provider profile in MediFind’s doctor database includes information on which conditions they treat, years of experience, research contributions, languages spoken, insurance plans accepted, and more.  

    How do I find the best Major Depression doctor near Spartanburg, SC?

    You can find a Major Depression doctor in any of the 10 largest U.S. cities by clicking below:

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    How does MediFind rank Major Depression doctors near Spartanburg, SC?

    MediFind’s rankings are based on a variety of data sources, such as the number of articles a doctor has published in medical journals, participation in clinical trials and industry conferences, as well as the number of patients that provider sees for a given condition. Note that MediFind’s provider database is not based on user reviews, and providers do not pay to be included in the database. 

    What types of insurance are accepted by Major Depression doctors near Spartanburg, SC?

    Most profiles in MediFind’s doctor database include a list of insurance plans accepted by that provider. However, it’s a good idea to contact the provider’s office to make sure they still accept your insurance, then doublecheck by contacting your insurance plan to confirm they’re in network. 

    How can I book an appointment online with a Major Depression doctor near Spartanburg, SC?

    MediFind offers direct scheduling for certain providers using the “Request Appointment” button on that provider’s profile. If the schedule option is not available for a provider, tap the red “Show Phone Number” button on their profile to get their contact information. If you prefer to find providers who offer online scheduling, select “Schedules online” under the “Availability” category of the filter feature on the left side of the Major Depression doctor search results page. 

    Why is it important to get a second opinion from a different Major Depression doctor?

    Second opinions are an opportunity to confirm a diagnosis and its root cause, learn about alternative treatment options, or simply gain peace of mind. Many people, especially those with serious diagnoses, get second opinions so they can understand all their options and make informed decisions, so don’t hesitate to get one if you have any doubts or need more information or clarification regarding your care. Note that some insurance plans require second opinions, while others don’t cover second opinions, so be sure to confirm with your insurance provider first.   

    How can I prepare for my appointment with a Major Depression doctor near Spartanburg, SC?

    Prepare for your appointment by gathering the following items: 

    • Copies of medical records (dating back at least one year) 
    • Your medical history, including illnesses, medical conditions, surgeries, and other doctors you see 
    • Family history of disease 
    • List of current prescription drugs, over-the-counter medicines, vitamins, and herbal remedies or supplements including names and doses 
    • Allergies to medications, food, latex, insects, etc.  
    • List of questions and concerns 
    • Your insurance card 

    You might also contact the provider’s office to see if they offer transportation or childcare services or if you’re allowed to bring a loved one for support or to take notes during your visit. 

    What questions should I ask my Major Depression doctor?

    Here are some sample questions: 

    • Can you explain in simple terms what this condition is and how it’s treated? 
    • What symptoms or side effects should I watch for? 
    • What tests will be involved, and when can I expect results? 
    • Are there other specialists I need to see? 
    • What’s the best way to reach you if I have follow-up questions? 

    How can I learn about the latest clinical trials and research advances my Major Depression doctor may know about?

    MediFind’s Clinical Trials tool asks you a series of questions to help you narrow down your search by health condition, age, gender, location, how far you’re willing to travel, and more. Each question you answer filters down the number of trials until you find the ones that are most relevant to you. 

    MediFind’s Latest Advances tool features summaries of recent articles published in medical journals. We use cutting-edge technology to scour medical publication databases for the latest research advancements on any given condition, then we simplify this information in a way that’s useful and easy to understand. 

    Can I filter my search to show male or female Major Depression doctors near Spartanburg, SC?

    Look for the filter feature on the left side of the Major Depression doctor search results page. Select “Female” or “Male” under the “Gender” category to search for female or male providers exclusively. If the “Any” option is selected, it will pull results for both male and female providers. 

    Can I filter my search to find a Major Depression doctor that offers video calls?

    Look for the filter feature on the left-side of the Major Depression doctor search results page. Select “Offers telehealth visits” under the Availability category to search for providers who offer virtual appointments (video calls). 

    Reviewed on: 11/11/24  

    By: MediFind Medical Staff 

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