The 20 Best Megalencephalic Leukoencephalopathy with Subcortical Cysts Doctors Near Me in Pittsburgh, PA

Find the Top Megalencephalic Leukoencephalopathy with Subcortical Cysts Experts and Specialists

Last Updated: 04/28/2026

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MediFind found 5 doctor with experience in Megalencephalic Leukoencephalopathy with Subcortical Cysts near Pittsburgh, PA. Of these, 4 are Experienced and 1 are Advanced.

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5 providers found
    Advanced in Megalencephalic Leukoencephalopathy with Subcortical Cysts
    Pediatrics
    Advanced in Megalencephalic Leukoencephalopathy with Subcortical Cysts
    Pediatrics

    Medical Genetics Metabolic In Lawrenceville

    4401 Penn Avenue, 
    Pittsburgh, PA 
     (3.0 miles away)
    Languages Spoken:
    English

    Damara Ortiz, MD, specializes in medical genetics and pediatric genetics and genomics and is board-certified in pediatrics by the American Board of Pediatrics and clinical genetics by the American Board of Medical Genetics and Genomics. She is affiliated with UPMC Children's Hospital of Pittsburgh, UPMC Magee-Womens Hospital and UPMC Presbyterian. Dr. Ortiz completed her fellowship at Icahn School of Medicine at Mount Sinai, residency at NYU Langone Medical Center and medical degree from the University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School. Dr. Ortiz is rated as an Advanced provider by MediFind in the treatment of Megalencephalic Leukoencephalopathy with Subcortical Cysts. She is also highly rated in 3 other conditions, according to our data. Her clinical expertise encompasses Fabry Disease, Megalencephalic Leukoencephalopathy with Subcortical Cysts, Multiple Sulfatase Deficiency, and Gaucher Disease. Dr. Ortiz is board certified in American Board Of Pediatrics and American Board Of Medical Genetics And Genomics.

    Experienced in Megalencephalic Leukoencephalopathy with Subcortical Cysts
    Experienced in Megalencephalic Leukoencephalopathy with Subcortical Cysts

    University Of Pittsburgh Physicians, Department Of Neurology

    3471 5th Avenue, Suite 810, 
    Pittsburgh, PA 
     (2.2 miles away)
    Languages Spoken:
    English
    Accepting New Patients
    Offers Telehealth

    Mary A. O'Neal, MD, specializes in neurology and is board-certified in neurology by the American Board of Psychiatry and Neurology. Dr. O'Neal completed her fellowship and residency at Boston University Medical Center and medical degree at Oregon Health & Science University. Dr. O'neal is rated as an Experienced provider by MediFind in the treatment of Megalencephalic Leukoencephalopathy with Subcortical Cysts. She is also highly rated in 16 other conditions, according to our data. Her clinical expertise encompasses Migraine with Brainstem Aura, Conversion Disorder, Migraine, and Headache. Dr. O'neal is board certified in American Board Of Psychiatry And Neurology. Dr. O'neal is currently accepting new patients.

    Experienced in Megalencephalic Leukoencephalopathy with Subcortical Cysts
    Experienced in Megalencephalic Leukoencephalopathy with Subcortical Cysts

    UPMC Kidney Clinic

    120 Lytton Avenue, Suite 201, 
    Pittsburgh, PA 
     (2.2 miles away)
    Languages Spoken:
    English
    Accepting New Patients
    Offers Telehealth

    Cary Shiwarski, MD, PhD, is certified in internal medicine and nephrology by the American Board of Internal Medicine. She practices at UPMC Kidney Clinic at University Center and is affiliated with UPMC Presbyterian, UPMC Mercy, UPMC Magee-Womens Hospital, and UPMC Shadyside. She completed her fellowship, residency, and medical degree at University of Pittsburgh School of Medicine.Are you already a patient of this provider and have a MyUPMC account? Log in to MyUPMC to schedule. Dr. Shiwarski is rated as an Experienced provider by MediFind in the treatment of Megalencephalic Leukoencephalopathy with Subcortical Cysts. Her clinical expertise encompasses End-Stage Renal Disease (ESRD), Chronic Kidney Disease, Fabry Disease, and Megalencephalic Leukoencephalopathy with Subcortical Cysts. Dr. Shiwarski is board certified in American Board Of Internal Medicine and American Board Of Internal Medicine. Dr. Shiwarski is currently accepting new patients.

    Learn about our expert tiers
    Experienced in Megalencephalic Leukoencephalopathy with Subcortical Cysts
    Medical Genetics | Pediatrics
    Experienced in Megalencephalic Leukoencephalopathy with Subcortical Cysts
    Medical Genetics | Pediatrics
    4401 Penn Ave, 
    Pittsburgh, PA 
     (3.0 miles away)
    Languages Spoken:
    English
    Accepting New Patients

    Jirair Bedoyan is a Medical Genetics specialist and a Pediatrics provider practicing medicine in Pittsburgh, Pennsylvania. Dr. Bedoyan is rated as an Experienced provider by MediFind in the treatment of Megalencephalic Leukoencephalopathy with Subcortical Cysts. He is also highly rated in 6 other conditions, according to our data. His clinical expertise encompasses Pyruvate Dehydrogenase Deficiency, Pyruvate Decarboxylase Deficiency, Dihydrolipoamide Dehydrogenase Deficiency, Urea Cycle Disorders (UCD), and Gastrostomy. Dr. Bedoyan is currently accepting new patients.

    Experienced in Megalencephalic Leukoencephalopathy with Subcortical Cysts
    Hematology Oncology
    Experienced in Megalencephalic Leukoencephalopathy with Subcortical Cysts
    Hematology Oncology

    St. Clair Hospital Cancer Center, Affiliated With UPMC Hillman Cancer Center

    1000 Bower Hill Road, Suite 7700, 
    Pittsburgh, PA 
     (5.9 miles away)
    Languages Spoken:
    English
    Accepting New Patients
    Offers Telehealth

    Christopher R. Marsh, MD, is a medical oncologist and hematologist specializing in the treatment of GI malignancies, including colorectal, pancreatic, and liver cancers. Dr. Marsh is rated as an Experienced provider by MediFind in the treatment of Megalencephalic Leukoencephalopathy with Subcortical Cysts. He is also highly rated in 32 other conditions, according to our data. His clinical expertise encompasses Paget Disease of the Breast, Inflammatory Breast Cancer, Lung Cancer, and Pleuropulmonary Blastoma. Dr. Marsh is board certified in American Board Of Internal Medicine and American Board Of Internal Medicine. Dr. Marsh is currently accepting new patients.

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    Last Updated: 04/28/2026

    What is the definition of Megalencephalic Leukoencephalopathy with Subcortical Cysts?

    Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a condition that affects brain development and function. Individuals with this condition have an enlarged brain (megalencephaly) and an abnormality of the white matter in the brain (leukoencephalopathy). White matter consists of nerve fibers covered by a fatty substance called myelin that promotes the rapid transmission of nerve impulses. In MLC, the myelin is swollen and contains numerous fluid-filled pockets (vacuoles). Over time, the swelling decreases and the myelin begins to waste away (atrophy). Leukoencephalopathy can lead to abnormal muscle tensing (spasticity), difficulty coordinating movements (ataxia), cysts in the brain (subcortical cysts), abnormal muscle tone (dystonia), swallowing difficulties, mild to moderate intellectual disabilities, speech difficulties, seizures, and difficulties walking. There are three types of MLC, which are distinguished by their signs and symptoms and genetic cause. Type 1 is caused by genetic changes in the MLC1 gene. Types 2A and 2B are caused by genetic changes in the HEPACAM gene. MLC types 1 and 2A are inherited in an autosomal recessive manner, while type 2B is inherited in an autosomal dominant manner. In some cases of MLC, the cause is unknown.

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