Prospective Observational Study to Compare Hemodynamic Alterations in Severe Aortic Stenosis and Severe Mitral Regurgitation After High Spinal Anesthesia in Patients Undergoing Aortic Valve and Mitral Valve Replacement Surgery
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY
This study will assess hemodynamic changes induced after spinal anesthesia by evaluating vasopressor inotropic requirements and variations in echocardiographic parameters in patients having severe aortic stenosis or severe mitral regurgitation undergoing aortic or mitral valve replacement surgery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:
• All patients over 18 years of age, irrespective of their gender or ASA physical status
• With severe aortic stenosis or mitral regurgitation
• Undergoing elective aortic or mitral valve repair or replacement
• Eligible for spinal anesthesia up to T1-2 level block for their surgical procedure.
• Able to provide written informed consent
Locations
Other Locations
Canada
Department of Anesthesiology, Perioperative and Pain Medicine, SBGH
RECRUITING
Winnipeg
Contact Information
Primary
Virendra Arya, MD, FRCPC
varya@sbgh.mb.ca
204 235-3659
Backup
Linda Girling, BSc Hons
lgirling@hsc.mb.ca
204 787-1414
Time Frame
Start Date: 2023-11-01
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 40
Treatments
Severe aortic stenosis group
Patients with severe aortic stenosis who are undergoing open aortic valve replacement under high spinal in combination with light general anesthesia.
Severe mitral regurgitation group
Patients with severe mitral regurgitation who are undergoing open mitral valve replacement under high spinal in combination with light general anesthesia.
Related Therapeutic Areas
Sponsors
Leads: University of Manitoba