Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of the study is to explore the feasibility of using a wearable device, called a myoelectric-computer interface (MCI), to improve arm movement in people who have had a stroke. Impaired arm movement after stroke is caused not just by weakness, but also by impaired coordination between joints due to abnormal co-activation of muscles. These abnormal co-activation patterns are thought to be due to abnormal movement planning.The MCI aims to reduce abnormal co-activation by providing feedback about individual muscle activations. This randomized, controlled, blinded study will test the home use of an MCI in chronic and acute stroke survivors.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Healthy Volunteers: f
View:

⁃ Chronic stroke participants

• Hemiparesis from first ever stroke at least 6 months prior to screening

• Severe motor impairment (FMA of 7-30)

• At least some voluntary shoulder and elbow muscle activation.

⁃ Acute stroke participants

• Hemiparesis from first ever stroke within the past 21 days

• Severe motor impairment (FMA of 3-20), or total Manual Motor Score of 1-8 combined in Shoulder Abduction and Finger Extensors

Locations
United States
Illinois
Northwestern University
RECRUITING
Chicago
Contact Information
Primary
Marc W Slutzky, MD, PhD
mslutzky@northwestern.edu
3125034653
Backup
Cynthia Gorski
cynthia.gorski@northwestern.edu
Time Frame
Start Date: 2018-01-15
Estimated Completion Date: 2025-12
Participants
Target number of participants: 96
Treatments
Experimental: Chronic stroke MCI Electromyogram (EMG) pairs
Decoupling 2 muscles at a time with MCI
Experimental: Chronic stroke MCI EMG triplets
Decoupling 3 muscles at a time with MCI
Experimental: Chronic stroke MCI while reaching
Decoupling muscles with MCI while reaching to targets
Sham_comparator: Chronic stroke Sham MCI
Sham control group
Experimental: Acute stroke MCI
Decoupling muscles with MCI in acute stroke subjects
Sham_comparator: Acute stroke Sham MCI
Acute stroke subjects sham comparator
Sponsors
Collaborators: Shirley Ryan AbilityLab, National Institutes of Health (NIH)
Leads: Northwestern University

This content was sourced from clinicaltrials.gov

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