Feasibility and Preliminary Effectiveness of Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) + Functional Strength Training (FST) in Children With Spinal Muscular Atrophy (SMA): a Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This single-arm pilot study will assess the feasibility and preliminary effectiveness of an intensive motor skill intervention (HABIT-ILE) combined with functional strength training (FST) in children with SMA who are receiving disease-modifying therapies. Participants will attend one 6-hour HABIT-ILE + FST session each weekend (Saturday or Sunday) for 15 weeks, for a total of 90 hours of training. Feasibility will be evaluated through questionnaires, and effectiveness through standardized motor function assessments.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 17
Healthy Volunteers: f
View:

• Diagnosis of SMA

• Able to participate in all pre and post intervention assessments

• Able to understand and speak English

• Able to understand directions (no significant cognitive delay or serious behavioral issues that would limit participation)

• Receiving a stable dose of disease-modifying therapies for at least 6 months prior to enrollment.

Locations
United States
New York
Center for Cerebral Palsy Research, Teachers College, Columbia University
RECRUITING
New York
Contact Information
Primary
Andrew M Gordon, PhD
ag275@tc.columbia.edu
+1(212) 678-3332
Backup
Astrid Carton de Tournai, PhD
apc2187@tc.columbia.edu
Time Frame
Start Date: 2025-10-01
Estimated Completion Date: 2027-07-01
Participants
Target number of participants: 5
Treatments
Experimental: Combined HABIT-ILE + FST
Participants receive a combined intervention consisting of Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) and Functional Strength Training (FST). Both components are delivered as an integrated, intensive motor learning-based program aimed at improving upper and lower limb function in children with SMA .Subject will participate in a HABIT-ILE + FST camp format for 6 hours/day, one day/week for 15 weeks.
Sponsors
Leads: Teachers College, Columbia University

This content was sourced from clinicaltrials.gov