Efficacy of a Myocardial Panel (Virological, Bacterial and Autoimmune) in the Management and Treatment of Pediatric Myocarditis Complicated With Arrhythmias or Ventricular Dysfunction

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this observational study is to determine the efficacy a of combined management and treatment driven by the systematic determination of viral genome, bacterial serology, and markers of inflammation in pediatric patients (\< 18 years old) diagnosed with myocarditis complicated by arrhythmias (supraventricular and ventricular tachycardias and heart block) or ventricular dysfunction (left ventricular ejection fraction \< 50% or right ventricular fractional area change \< 35%). The main question it aims to answer is: Does this panel help resolve arrhythmias or myocardial dysfunction due to myocarditis during hospitalisation and follow-up? Researchers will compare patients managed and treated in 2024 without applying the myocarditis panel with those enrolled in 2025 who received the panel. Arrhythmias and myocardial dysfunction will be managed in accordance with recent guidelines. Antiviral, antibiotic or immunosuppressive therapies will be implemented in addition to standard therapy when required by the panel.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 18
Healthy Volunteers: f
View:

• All the consecutive pediatric patients (\< 18 years old) presenting with myocarditis complicated by arrhythmias or myocardial dysfunction

Locations
Other Locations
Italy
Francesco Bianco
RECRUITING
Ancona
Contact Information
Primary
Francesco Bianco, M.D., Ph.D., MSc, FEACVI
francesco.bianco@ospedaliriuniti.marche.it
+39 071 596 5527
Time Frame
Start Date: 2024-01-01
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 30
Treatments
Experimental: Myocarditis Panel
N=15 patients from 2025, in which management and treatment of arrhythmias and or myocardial dysfunction were driven by the panel
No_intervention: No Panel
The 15 patients managed and treated for arrhythmias or myocardial dysfunction in 2024 without applying the myocarditis panel
Sponsors
Leads: Azienda Ospedaliero, Universitaria Ospedali Riuniti

This content was sourced from clinicaltrials.gov