Induction Chemotherapy+Chemoradiotherapy vs. Chemoradiotherapy for Locally Advanced Nasopharyngeal Carcinoma
Who is this study for? Patients with locally advanced nasopharyngeal carcinoma
Status: Recruiting
Location: See location...
Intervention Type: Drug, Radiation
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
This trial is a multi-center phase III clinical trial. The purpose of this trial is to explore whether concurrent chemoradiotherapy is not inferior to induction chemotherapy combined with concurrent chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• Age 18-65 years old;
• Pathologically confirmed non-keratinizing nasopharyngeal carcinoma;
• Stage T3-4N0-1 (according to the UICC/AJCC 8th);
• No distant metastasis;
• Have not received anti-cancer treatment in the past;
• ECOG (Eastern Cooperative Oncology Group of the United States): 0-1;
• Adequate hematologic, hepatic and renal function.
Locations
Other Locations
China
The First Affiliated Hospital of Sun Yat-sen University
RECRUITING
Guangzhou
Contact Information
Primary
Shuang Wu, PHD
wush77@mail.sysu.edu.cn
+862087755766
Time Frame
Start Date: 2021-09-22
Estimated Completion Date: 2027-08-31
Participants
Target number of participants: 447
Treatments
Other: Induction Chemotherapy+Chemoradiotherapy
Other: Chemoradiotherapy
Related Therapeutic Areas
Sponsors
Leads: First Affiliated Hospital, Sun Yat-Sen University