Endoscopic NBI Combined With MRI to Guide the Optimization of Clinical Target Volume Delineation in Eccentric Nasopharyngeal Carcinoma
This is a prospective, single-center clinical trial in eccentric nasopharyngeal carcinoma (NPC) patients. The aim of this study is to evaluate the efficacy and safety of NBI combined with MRI-guided optimized CTV compared with conventional CTV, and to compare the radiotherapy-related adverse events and quality of life between the two groups.
• Males and females ≥18 years of age;
• ECOG Performance Status 0,1 or 2;
• Pathologically diagnosed as nasopharyngeal carcinoma;
• Pretreatment nasopharynx and neck MRI imaging;
• Nasopharyngeal suspected lesions were examined by NBI endoscopy;
• Meeting the definition of eccentric NPC with ipsilateral (affected side) staging of T1-4 and contralateral (healthy side) staging of T0;
• Patients evaluated without contraindications to radiotherapy;
• Voluntary participation in clinical research, and signed informed consent.