Pancreatitis - Microbiome as Predictor of Severity II
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The goal of this observational study is to evaluate the orointestinal microbiome and microbial derived metabolome in patients suffering from acute pancreatitis as a biomarker for severity. The main questions it aims to answer are: * Can the orointestinal microbiome robustly predict the course of acute pancreatitis? * How does the microbiome impact the severity of an acute pancreatitis? Buccal/ rectal swabs, plasma and stool is collected from patients with acute pancreatitis within 48h after hospital admission.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients with initial diagnosis (\< 48h) of acute pancreatitis
• Age ≥ 18 years
• Patients able to understand/ give their written consent
Locations
Other Locations
Germany
University Medical Center Goettingen
RECRUITING
Göttingen
Contact Information
Primary
Christoph Ammer-Herrmenau, Dr
christoph.herrmenau@med.uni-goettingen.de
+491704075339
Backup
Jacob Hamm, Dr
jacob.hamm@med.uni-goettingen.de
+495513963231
Time Frame
Start Date: 2024-05-01
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 700
Treatments
Revised Atlanta classifiaction (RAC) I - mild
No local or systemic complication
Revised Atlanta classifiaction (RAC) II - moderate severe
Local complications as necrosis or fluid collection or organ failure \< 48h
Revised Atlanta classifiaction (RAC) III - severe
Organ failure \> 48h
Related Therapeutic Areas
Sponsors
Leads: University Medical Center Goettingen