The Validity of the Quick Renal MRI in Pediatric Kidney Disease

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The investigators propose a new imaging method for children born with congenital anomalies of the urinary tract that is a rapid, injection-, sedation-, and radiation-free alternative: the quick renal MRI. This proposal hypothesizes that the quick renal MRI has high validity compared to current radiologic standard for renal infection and scarring, the 99mTechnetium-dimercaptosuccinic acid (99mTc- DMSA) renal scan in the detection of acute renal infections and scars. If the quick renal MRI is accurate, it could potentially replace the DMSA scan for those specific questions and ease the burden of testing for children with chronic renal disease. Findings from these studies will provide preliminary data and rationale for a multi-centered study to further test this new technology. Participants will be 0-21 years of age and can expect to be on study for from 1 week (if enrolled in Aim 1) to 6 months (if enrolled in Aim 2).

Eligibility
Participation Requirements
Sex: All
Maximum Age: 21
Healthy Volunteers: f
View:

• Aim 1:

‣ Patient is admitted to American Family Children's Hospital for a febrile UTI, suspected pyelonephritis, or diagnosed pyelonephritis

⁃ Undergoing clinical DMSA scan

• Aim 2:

‣ Undergoing DMSA scans as a part of their routine clinical care

⁃ History of more than one UTI in the past year

Locations
United States
Wisconsin
American Family Children's Hospital
RECRUITING
Madison
Contact Information
Primary
Shannon Cannon, MD
cannon@urology.wisc.edu
(608) 265-8574
Time Frame
Start Date: 2019-05-07
Estimated Completion Date: 2025-01
Participants
Target number of participants: 100
Treatments
Other: DMSA/Quick MRI
All participants will go through DMSA and Quick MRI scan to help determine the validity of the Quick Renal MRI in pediatric kidney disease.
Authors
Ruthie Su
Related Therapeutic Areas
Sponsors
Leads: University of Wisconsin, Madison

This content was sourced from clinicaltrials.gov

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