Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS, and finally 3) whether different SCS waveforms elicits stimulus-evoked compound action potentials (ECAPs) in spinal cord and at the cortex (electroencephalography, and magnetoenchphalography).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 89
Healthy Volunteers: f
View:
• Male or Female, age 18-89
• Chronic pain for more than 3 months
• Willing to visit a research lab
• Willing to undergo a blood draw
• Able to provide written informed consent
Locations
United States
Alabama
University of Alabama at Birmingham
RECRUITING
Birmingham
Contact Information
Primary
Chris Gonzalez, MS
clgonzalez@uabmc.edu
(205) 975-3732
Time Frame
Start Date: 2022-08-02
Estimated Completion Date: 2030-05-01
Participants
Target number of participants: 80
Treatments
Experimental: Treatment
Patients that proceed with permanent implantation of a spinal cord stimulator.
No_intervention: Control
Patients who do not proceed with permanent implantation of a spinal cord stimulator.
Related Therapeutic Areas
Sponsors
Leads: University of Alabama at Birmingham