Trigeminal Evoked Responses to Improve Rhizotomy

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY

Trigeminal neuralgia (TGN) is a debilitating pain syndrome where electrical, shock- like jolts of pain affect the face. Trigeminal somatosensory evoked potentials (TSEPs) provide a promising modality for measuring the trigeminal sensory and nociceptive pathway by using peripheral stimulation of the trigeminal nerve (on the skin) and measuring low latency evoked potentials on the scalp (contralateral sensory cortex). While TSEPs have been measured in the past, it is not clear if implementing TSEPs into a routine neurosurgical rhizotomy procedure will be feasible. This is a prospective cohort study examining the feasibility of routinely performing TSEPs during rhizotomies for TGN.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Adults of 18 years or older

• Scheduled to undergo percutaneous rhizotomy for facial pain

Locations
United States
Minnesota
University of Minnesota
RECRUITING
Minneapolis
Contact Information
Primary
Danielle Carlson, MD
carl1492@umn.edu
612-626-3582
Time Frame
Start Date: 2023-11-01
Estimated Completion Date: 2026-11-01
Participants
Target number of participants: 30
Treatments
Experimental: TGN patients
Patients with TGN who will undergo rhizotomy surgery as the standard of care
Active_comparator: Healthy volunteers
Healthy volunteers for whom TSEPS will be recorded in a lab setting
Sponsors
Leads: University of Minnesota

This content was sourced from clinicaltrials.gov

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