The Efficacy of Ultrasound-guided Pecto-Intercostal Fascial Plain Block Versus Lidocaine Infusion on Acute and Chronic Post-thoracotomy Pain; A Prospective Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Procedure, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Chronic pain is a common complication after cardiothoracic surgery. The prevalence of post-thoracotomy pain syndrome (PTPS) ranges from 33% to 91%. Exact pathogenetic mechanisms for developing chronic pain after thoracotomy are unknown. Apart from intraoperative nerve damage and subsequent postoperative neuropathic pain, operation techniques, age, sex, pre-existing pain, genetic and psychosocial factors, severe postoperative pain, and analgesic management are suspected to have an impact on the development of PTPS .
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: t
View:
• age between 18 and 75 years.
• patient scheduled to undergo elective on-pump cardiac surgery with sternotomy.
• American Society of Anesthesiologists classification of physical status \< IV.
Locations
Other Locations
Egypt
Benisuef University Hospital
RECRUITING
Banī Suwayf
Contact Information
Primary
Mariana A soliman, lecturer
mrmrsyk4@gmail.com
01222960009
Time Frame
Start Date: 2023-05-01
Estimated Completion Date: 2024-05
Participants
Target number of participants: 138
Treatments
Active_comparator: PIFB group
patients will receive bilateral ultrasound-guided pecto-intercostal fascial block using 20 ml of bupivacaine 0.25% for each side.
Active_comparator: LIDOCAINE group
1.5 mg/kg lidocaine will be administered after induction of anesthesia, then 2mg/kg/h lidocaine will be administered with continuous intravenous infusion until the end of the surgery.
Related Therapeutic Areas
Sponsors
Leads: Beni-Suef University