Pilot Study of 68Ga-DOTATATE PET/CT and 123I-MIBG Scintigraphy Imaging of Neuroblastoma

Who is this study for? Patients with Neuroblastoma
What treatments are being studied? Radiopharmaceutical 68Ga-DOTATATE
Status: Recruiting
Location: See all (3) locations...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

Neuroblastoma is the most frequent extracranial childhood tumor, with an annual incidence of approximately 10.2 per million children. Staging of the disease can be done by different imaging strategies (CT, MRI, scintigraphy and PET/CT). Discrepancies may be observed among these different strategies resulting in different treatment strategies. The goal of this study is to assess the feasibility and safety of 68Ga-DOTATATE and to compare it to 123I-MIBG when investigating neuroblastoma.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 21
Healthy Volunteers: f
View:

• Newly suspected or biopsy-proven neuroblastoma or recurrence of neuroblastoma

• Planned 123I-MIBG imaging

• Able and willing to provide signed informed consent in French or English (for the adult candidates or the parent/legal tutor of the pediatric candidates)

• Aged between 1 day and 21 years old (inclusively).

Locations
Other Locations
Canada
CHU Ste-Justine
RECRUITING
Montreal
McGill University Health Center - Children's hospital
WITHDRAWN
Montreal
CIUSSS de l'Estrie-CHUS Hospital
RECRUITING
Sherbrooke
Contact Information
Primary
Amelie Tetu, MSc
amelie.tetu.ciussse-chus@ssss.gouv.qc.ca
819-346-1110
Time Frame
Start Date: 2021-12-06
Estimated Completion Date: 2027-09-30
Participants
Target number of participants: 20
Treatments
Experimental: Single arm with 68Ga-DOTATATE
all participants will undergo a PET scan with 68Ga-DOTATATE
Sponsors
Leads: Centre de recherche du Centre hospitalier universitaire de Sherbrooke

This content was sourced from clinicaltrials.gov