A Randomized Phase II Trial Evaluation of the Addition of the Resource Intervention to Support Equity (RISE) to Usual Supportive Care for Children With Newly Diagnosed High-Risk Neuroblastoma
The goal of this study is to test if the addition of a novel income-poverty targeted supportive care intervention (Pediatric Resource Intervention to Support Equity \[Pediatric RISE\]) to usual supportive care for low-income children with high-risk neuroblastoma can improve parent- and child-centered outcomes. Participants will be randomized to receive one of the following for 6-months: * Usual supportive care alone or * Usual supportive care plus Pediatric RISE
⁃ Patient cohort: The randomized Phase II multi-center RISE intervention will be conducted among a population of poverty-exposed children with high-risk neuroblastoma. Poverty will be a priori defined as parent-reported low-income (\<200% Federal Poverty Level). Children receiving treatment for cancer at study sites will serve as the study cohort, with parents/guardians as survey informants and intervention recipients on behalf of their minor children given that parents (not children) typically manage household finances.
• Patient newly diagnosed with high-risk neuroblastoma
• Patient has established care at study site and initiated cancer-directed therapy
• Patient has not yet initiated Induction Cycle 3
• Patient aged 0-17 years at the time of consent
• Parent/guardian screened positive for self-reported low-income (\<200% Federal Poverty) \*
• Family primary residence in MA, PA, IL, CA, WA, CT, GA, WI and OH
• Both patients co-enrolled on ANBL2131 or those receiving standard of care therapy at their center are eligible to participate
• Patients of all languages are eligible to participate