Medications for Neuroblastoma
These are drugs that have been approved by the US Food and Drug Administration (FDA), meaning they have been determined to be safe and effective for use in Neuroblastoma.
Found 5 Approved Drugs for Neuroblastoma
DOXOrubicin
Brand Names
Doxil, Adriamycin
DOXOrubicin
Brand Names
Doxil, Adriamycin
Form: Injection, Injectable
Method of administration: Intravenous, Intravitreal
FDA approval date: December 23, 1987
Classification: Anthracycline Topoisomerase Inhibitor
Doxorubicin is an anthracycline topoisomerase II inhibitor indicated: as a component of multiagent adjuvant chemotherapy for treatment of women with axillary lymph node involvement following resection of primary breast cancer.
Unituxin
Generic Name
Dinutuximab
Unituxin
Generic Name
Dinutuximab
Form: Injection
Method of administration: Intravenous
FDA approval date: March 10, 2015
Classification: Glycolipid Disialoganglioside-directed Antibody
Unituxin (dinutuximab) is indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy. Unituxin is a GD2-binding monoclonal antibody indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2), and 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who achieve at least a partial response to prior first-line multiagent, multimodality therapy. ( 1 )
Eflornithine
Brand Names
Iwilfin, Florexa
Eflornithine
Brand Names
Iwilfin, Florexa
Form: Cream, Tablet
Method of administration: Oral, Topical
FDA approval date: February 09, 2012
Classification: Antiprotozoal
Florexa is indicated for the reduction of unwanted facial hair in women. Florexa has only been studied on the face and adjacent involved areas under the chin of affected individuals. Usage should be limited to these areas of involvement.
Danyelza
Generic Name
Naxitamab
Danyelza
Generic Name
Naxitamab
Form: Injection
Method of administration: Intravenous
FDA approval date: November 25, 2020
Classification: Glycolipid Disialoganglioside-directed Antibody
DANYELZA is indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), for the treatment of pediatric patients 1 year of age and older and adult patients with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow who have demonstrated a partial response, minor response, or stable disease to prior therapy. This indication is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). DANYELZA is a GD2-binding monoclonal antibody indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), for the treatment of pediatric patients 1 year of age and older and adult patients with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow who have demonstrated a partial response, minor response, or stable disease to prior therapy. This indication is approved under accelerated approval based on overall response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s). ( 1 )
AdreView
Generic Name
Iobenguane I-123
AdreView
Generic Name
Iobenguane I-123
Form: Injection
Method of administration: Intravenous
FDA approval date: September 19, 2008
AdreView is a radiopharmaceutical agent for gamma-scintigraphy indicated for: use in the detection of primary or metastatic pheochromocytoma or neuroblastoma as an adjunct to other diagnostic tests.
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