Impact of Obesity on Post-operative Cognitive Dysfunction: Role of Adipose Tissue
Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Observational
SUMMARY
This research aims at describing the relationship between white adipose tissue inflammation and post-operative cognitive dysfunctions.The possible link between inflammatory cytokines secretions of the white adipose tissue of a surgical wound and the arising of patient's cognitive dysfunction in the post-operative course will be investigated. The hypothesis is that obese patient's inflammation of the white adipose tissue leads to cognitive dysfunction.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Maximum Age: 99
Healthy Volunteers: f
View:
• patient about to receive a hip arthroplasty under general anesthesia, elective cardiac surgery with cardiopulmonary bypass,
• patient with a MMSE score \> or = 20(/30),
• patient able to give informed consent
Locations
Other Locations
France
Purpan University Hospital
RECRUITING
Toulouse
Contact Information
Primary
François Labaste, MD, PhD
labaste.f@chu-toulouse.fr
561322822
Time Frame
Start Date: 2021-09-21
Estimated Completion Date: 2025-09-21
Participants
Target number of participants: 408
Treatments
Obese patients
BMI \>30kg/m2
non obese patients
BMI between 18 to 29kg/m2
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Toulouse