Biobehavioral Reward Responses Associated With Consumption of Nutritionally Diverse Ultra-Processed Foods
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The changing food environment, with increasingly abundant ultra-processed food (UPF) options, may directly contribute to rising rates of obesity, though it is unknown which ingredients in UPF elevate their reinforcing nature in a way that may lead to overconsumption. The proposed study is the first to systematically examine differences in the rewarding characteristics of and physiological and metabolic responses to UPFs that are high in fat, refined carbohydrates (like sugar), or both. Understanding the biobehavioral underpinnings that enhance the reinforcing potential of ingredients in UPF (e.g., fat vs. refined carbohydrates) can inform novel intervention targets for the treatment of overeating and obesity.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
Locations
United States
Pennsylvania
Drexel University
RECRUITING
Philadelphia
Contact Information
Primary
Erica M. LaFata, Ph.D.
elafata@ori.org
9136535022
Time Frame
Start Date: 2023-02-20
Estimated Completion Date: 2027-03-31
Participants
Target number of participants: 50
Treatments
Other: UPF high in fat and refined carbohydrates
This test snack condition consists of ultra-processed foods high in both fat and refined carbohydrates.
Other: UPF high in fat
This test snack condition consists of ultra-processed foods high in fat.
Other: UPF high in refined carbohydrates
This test snack condition consists of ultra-processed foods high in refined carbohydrates.
Other: MPF high in fat or carbohydrates
This test snack condition consists of minimally processed foods naturally high in either fat or carbohydrates.
Related Therapeutic Areas
Sponsors
Leads: Oregon Research Institute
Collaborators: Oregon Research Institute Community and Evaluation Services