Molecular Mechanisms Underpinning Sarcopenic Obesity
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Observational
SUMMARY
The coexistence of obesity and sarcopenia results in sarcopenic obesity, a high-risk geriatric condition associated with metabolic perturbations and several co-morbidities. Despite the rising numbers of older adults diagnosed with sarcopenic obesity, few studies have characterized this condition on the muscle cell and systemic level. This study sought to comprehensively assess the influence of sarcopenic obesity on muscle and blood-related parameters and compare it to non-sarocopenic obese and non-sarcopenic lean older adults.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
View:
• Body fat % in accordance with previously defined criteria
• Free of smoking (since 10 years)
• Able to walk without assistance
• Able to perform bilateral leg extension exercise
Locations
Other Locations
Sweden
The Swedish School of Sport and Health Sciences
RECRUITING
Stockholm
Contact Information
Primary
William Apró, PhD
william.apro@gih.se
08-120 538 67
Time Frame
Start Date: 2020-01-28
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 60
Treatments
Sarcopenic obesity
Age: 70-80 years Men, ALM/W \< 25.7 %, body fat % \> 35 Women, ALM/W \< 19.7 %, body fat % \> 40
Non-sarcopenic obese
Age: 70-80 years Men, ALM/W \> 25.7 %, body fat % \> 35 Women, ALM/W \> 19.7 %, body fat % \> 40
Non-sarcopenic lean
Age: 70-80 years Men, ALM \> 7.0 kg/m2, body fat % \< 25 Women, ALM \> 5.5 kg/m2, body fat % \< 32
Young lean
Age: 18-40 years Men, ALM \> 7.0 kg/m2, body fat % \< 25 Women, ALM \> 5.5 kg/m2, body fat % \< 32
Related Therapeutic Areas
Sponsors
Leads: The Swedish School of Sport and Health Sciences