EXercise Magnetic Resonance Imaging in Patients With Obesity aSsociated Heart failURe With Preserved Ejection Fraction (EXPOSURE) Study
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
To aim of the EXPOSURE study is to investigate the effects of epicardial fat on cardiac function, pericardial constraint and pulmonary artery vasodilatation using cardiac magnetic resonance (CMR) imaging at rest and during exercise stress testing in patients with HFpEF.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Signs and symptoms of HF according to the Europeans Society of Cardiology guideline.
• LV ejection fraction ≥40%.
• HFA-PEFF score ≥5 or HFA-PEFF score 2-4 in combination with positive stress test (Figure 1).
• \>18 years of age
• In sinus rhythm
• Able to perform a bicycle exercise test
• Willing to sign informed consent
Locations
Other Locations
Netherlands
University Medical Center Groningen
RECRUITING
Groningen
Contact Information
Primary
Thomas M Gorter, MD, PhD
tm.gorter@umcg.nl
+3150 361 6161
Time Frame
Start Date: 2024-01-16
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 50
Related Therapeutic Areas
Sponsors
Leads: University Medical Center Groningen