The Effect of Time-Restricted Feeding on Body Composition and Some Metabolic Parameters in Obese Adolescents

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Obesity is now recognized as a serious public health problem. It is known that obesity seen in adolescence is largely carried over to adulthood. Therefore, its treatment is important both in terms of protecting current health and preventing diseases in adulthood. Reducing energy intake plays an important role in the treatment of obesity. However, long-term adherence and effectiveness to energy restriction appear to be limited. Therefore, the need for interventions that are effective in body weight loss and accessible, simple and lifestyle modification to increase dietary compliance is clear. Time-restricted feeding is a specialized intermittent fasting protocol that includes consistent fasting and eating periods over a 24-hour cycle by supporting circadian rhythms. Especially in the adult population, positive effects of time-restricted feeding such as weight loss and blood glucose regulation are observed. However, there are limited data on this subject for adolescents. Today, the Mediterranean diet, which is one of the nutrition models that supports health, is a beneficial nutritional model that reduces body weight and obesity-related comorbidities by limiting total energy intake. However, no study has been found in the literature in which the effectiveness of time-restricted nutrition, which is a new and promising approach, and the Mediterranean diet, which is a sustainable diet model, are evaluated together. Therefore, in this study, it was aimed to evaluate the effects of planned time-restricted nutrition compatible with circadian rhythm and energy-restricted feeding planned according to the Mediterranean diet model on body composition and various metabolic parameters in obese adolescents. 60 obese adolescents aged 12-18 years will be included in this randomized controlled and parallel design study. Participants will be randomized to one of two treatment groups for a 12-week intervention. The time-restricted feeding group will form the intervention group of the study, and the energy-restricted feeding group will form the control group. Anthropometric measurements of the participants at the beginning and end of the study will be taken, and various biochemical parameters will be evaluated with the body composition and blood samples to be taken. As a result of the study, it is expected to determine the effectiveness of time-restricted feeding compared to energy-restricted feeding in terms of dietary compliance, body composition and biochemical changes.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 12
Maximum Age: 18
Healthy Volunteers: f
View:

• Adolescents aged 12-18 with puberty stage:5

• Obese adolescents with a metabolic disorder (such as fatty liver, insulin resistance, prediabetes, dyslipidemia) (BMI≥95th percentile for age)

• Those who have a stable body weight for 3 months before the start of the study (current weight gain or loss \<4 kg)

• Those who own and can use a Smartphone with Apple iOS or Android operating system

• Those who speak, read and understand Turkish

Locations
Other Locations
Turkey
Mustafa Eraslan and Fevzi Mercan Children's Hospital
RECRUITING
Kayseri
Contact Information
Primary
Sümeyra Başar
sumeyra_akalin@hotmail.com
+ 90 538 638 0089
Backup
Zeynep Caferoğlu Akın
zcaferoglu@erciyes.edu.tr
+90 537 766 3898
Time Frame
Start Date: 2024-10-14
Estimated Completion Date: 2025-08-15
Participants
Target number of participants: 60
Treatments
Experimental: Control group - Calorie-restricted feeding
Participants will be applied a nutrition plan prepared in line with the principles of the Mediterranean Diet without any time restrictions.
Experimental: Intervention group - Time restricted feeding
Participants will be applied with an ad libitum nutrition plan between 10:00 and 18:00.
Related Therapeutic Areas
Sponsors
Leads: Sümeyra Başar
Collaborators: Health Institutes of Turkey

This content was sourced from clinicaltrials.gov