Effect of a Family-Based Cognitive Behavioral Therapy Self-Help Intervention for Adolescents With Obsessive-Compulsive Disorder:A Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug, Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if self-help book can be used to treat obsessive-compulsive disorder (OCD) in adolescents aged 10 to 17. The main questions it aims to answer are: Can adolescents and their parents effectively reduce the severity of the obsessive-compulsive symptoms in adolescents who are already stably taking medications through self-help books? What are the characteristics of adolescents who are best suited to use self-help intervention book to treat obsessive-compulsive symptoms? Researchers will compare the use of a self-help books plus medication with medication alone to see if the combination of the self-help intervention and drug treatment can improve the obsessive-compulsive symptoms of adolescents more effectively. Participants will: * Read one chapter of a self-help book and complete the corresponding exercise each week for 12 weeks * Visit the clinic before and after intervention for checkups and tests

Eligibility
Participation Requirements
Sex: All
Minimum Age: 10
Maximum Age: 17
Healthy Volunteers: t
View:

• Age between 10 and 17 years

• Satisfied with the diagnostic criteria for OCD in DSM-5

• 16≤CY-BOCS score ≤23

• Taking medication stably for 6 weeks

• Education level ⩾6 years

• At least one parent can accompany the patients throughout the entire intervention process

• The patient and the participating parent have sufficient reading and writing skills to complete the treatment intervention

• The patient and the participating parent have adequate auditory and visual abilities skills to complete the necessary examinations for the study

⁃ (7) Right-handed (this criterion is for fMRI subjects only) (8) Subjects and their guardians understood the study and signed informed consent.

Locations
Other Locations
China
Shanghai Mental Health Center
RECRUITING
Xuhui
Contact Information
Primary
Yiwen Wu
wuyiwenhsd@163.com
+86 135 8590 0231
Backup
Xingyu Liu
xingyu_liu@sjtu.edu.cn
+86 134 5319 0989
Time Frame
Start Date: 2025-04-30
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 88
Treatments
Experimental: Family-Based Self-Help Intervention Group
Adolescents with OCD in this group will continue their stable pharmacological treatment for at least six weeks prior to enrollment. After baseline assessment, they will receive a 12-week structured cognitive behavioral therapy (CBT)-based self-help intervention, specifically designed for chinese adolescents and involving family participation. After the 12-week intervention, participants will enter a 3-month follow-up phase, during which no new therapeutic components will be introduced, but data on symptom maintenance and treatment adherence will be collected.During the 12-week intervention they will continue with the medications they already have.
Active_comparator: Treatment-As-Usual Waitlist Control Group
Adolescents with OCD in this group will be similarly required to receive at least six weeks of stabilizing medication prior to enrollment. In this group, participants will be treated as usual. Namely, they will continue with the medications they already have with no changes throughout the 12-week intervention period. No psychological intervention will be provided during this phase. After completing the follow-up assessment at week 12, participants will be offered access to the CBT-based self-help book as a delayed intervention.
Related Therapeutic Areas
Sponsors
Leads: Shanghai Mental Health Center

This content was sourced from clinicaltrials.gov