Exploring the Effects of Primary Open-Angle Glaucoma on Visual-Motor Coordination

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Commonly used visual function assessments in glaucoma diagnosis and treatment-such as visual acuity, visual field, and contrast sensitivity-do not directly capture the impact of the disease on patients' daily abilities. While questionnaires can evaluate this impact from the patient's perspective, they are subject to individual biases and inconsistent evaluation standards. Thus, objective methods are needed to assess patients' abilities in visually guided daily activities. Grasping objects and avoiding obstacles are fundamental visually guided tasks that require effective visuomotor coordination. By attaching lightweight reflective markers to participants' limbs and using a motion capture system to track their movements in three-dimensional space, various indicators of planning, execution, and control in tasks such as object grasping and obstacle avoidance can be quantified, allowing for an objective evaluation of visuomotor coordination. However, it remains unclear how visuomotor coordination is affected in glaucoma patients at different disease stages or whether visual field damage in specific areas has distinct impacts on visuomotor coordination. This study, therefore, aims to investigate changes in visuomotor coordination among patients with primary open-angle glaucoma across disease stages and to determine the effects of visual field defects in different locations on their visuomotor abilities.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: t
View:

• 1 Inclusion criteria of primary open-angle glaucoma group:

⁃ Age between 18 and 75 years;

⁃ Diagnosed with primary open-angle glaucoma, with no anti-glaucoma surgery scheduled within ±1 month;

⁃ Best corrected visual acuity in one eye ≥ 6/12;

⁃ Stereoscopic vision ≥ 1000 seconds of arc;

⁃ Able to clearly communicate and cooperate with the completion of relevant assessments and data collection.

• 2 Inclusion criteria of healthy controls:

⁃ Age between 18 and 75 years;

⁃ No history of eye disease other than refractive error and cataract;

⁃ Best corrected visual acuity in both eyes ≥ 6/12;

⁃ Stereoscopic vision ≥ 1000 seconds of arc;

⁃ Able to clearly communicate and cooperate with the completion of relevant assessments and data collection.

Locations
Other Locations
China
Zhongshan Opthalmic Center, Sun Yat-sen University
RECRUITING
Guangzhou
Contact Information
Primary
Yehong Zhuo
zhuoyh@mail.sysu.edu.cn
02066619349
Backup
Haishun Huang
huanghsh9@mail2.sysu.edu.cn
13229518626
Time Frame
Start Date: 2024-11-21
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 200
Treatments
Primary open-angle glaucoma
Patients with primary open-angle glaucoma diagnosed by glaucoma professionals
Healthy controls
Healthy controls were required to have a presenting Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity of 20/40 or better in both eyes.
Sponsors
Leads: Zhongshan Ophthalmic Center, Sun Yat-sen University

This content was sourced from clinicaltrials.gov