Opioid Use Disorder Clinical Trials

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Transcranial Magnetic Stimulation (TMS) to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD)

Status: Recruiting

Location: See location...

Intervention Type: Device

Study Type: Interventional

Study Phase: Not Applicable

SUMMARY

The study aims to explore the potential of Transcranial Magnetic Stimulation (TMS), particularly Theta Burst Stimulation (TBS), as an adjunctive treatment to enhance recovery outcomes (consumption and craving; withdrawal symptoms; mental, physical, sleep, and cognitive health; engagement with therapy, etc.) in individuals with Opioid Use Disorder (OUD) and individuals with Alcohol Use Disorder (AUD). This project will be completed in partnership with Another Chance Rehab (Portland): Portland's top addiction treatment program offering evidence-based treatment programs for a range of substance use disorders. Another Chance Rehab will serve as the project site for this work.

Eligibility

Participation Requirements

Sex: All

Minimum Age: 18

Healthy Volunteers: f

View:

• 18+ years old

• Enrolled in the Intensive Outpatient Program at Another Chance Drug \& Alcohol Rehab Center of Portland, Portland, OR.

• Diagnosed with Opioid Use Disorder

• Diagnosed with Alcohol Use Disorder

Locations

United States

Oregon

Another Chance Drug & Alcohol Rehab Center of Portland

RECRUITING

Portland

Contact Information

Primary

Matthew E Layton, MD, PhD

layton@wsu.edu

509-389-1108

Backup

Poppy M Gardiner, PhD

poppymay.gardiner@wsu.edu

509-428-4236

Time Frame

Start Date: 2027-06-01

Estimated Completion Date: 2027-10-01

Participants

Target number of participants: 60

Treatments

No_intervention: Treatment As Usual

Study participants in this arm will engage in intensive outpatient alcohol and addiction treatment provided as it usually is for all patients in this program.

Active_comparator: 3-Minute TMS

TAU + 3-minute TMS: Participants complete TAU as described above, with one 3-minute session of TMS TBS delivered each morning, prior to commencement of their regularly scheduled daily therapy activities, for 5 days/week, for a total of four-weeks (20 sessions total).

Active_comparator: 9-Minute TMS

TAU + 9-minute TMS: Participants complete TAU as described above, with one 9-minute session of TMS TBS delivered each morning, prior to commencement of their regularly scheduled daily therapy activities, for 5 days/week, for a total of four-weeks (20 sessions total).

Related Therapeutic Areas

Opioid Use Disorder

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