Histological Validation of dGEMRIC Indices as a Quantitative Biomarker for Cartilage Damage in the Hip Joint
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
In this study, the investigators seek to validate 3D model-based dGEMRIC (delayed gadolinium enhanced MRI of cartilage) values against histologic grading of cartilage quality, using osteochondral samples of the femoral head collected during hip replacement surgery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients with advanced hip osteoarthritis.
• Preoperative hip MRI including biochemical sequence (MP2RAGE).
• Indication for hip replacement.
Locations
Other Locations
Switzerland
University Hospital of Bern (Inselspital)
RECRUITING
Bern
Contact Information
Primary
Jose A. Roshardt, Dr.
jose.roshardt@insel.ch
+41316640440
Time Frame
Start Date: 2022-09-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 25
Related Therapeutic Areas
Sponsors
Leads: Insel Gruppe AG, University Hospital Bern