COSTI: COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty - A Triple Blinded, Randomized Controlled Trial Pilot Study
Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA. The secondary outcome was to assess the effect of contralateral corticosteroid injection on pain and functional outcomes of patients undergoing TKA.
• Patients 18 years of age and older
• Primary osteoarthritis diagnosis with indication for primary elective unilateral TKA
• No previous contralateral knee injections (steroids/biologics) within one year of study
• Not scheduled for bilateral TKA or a subsequent staged contralateral TKA within the next six months
• No previous or active infection or trauma (osseous/ligamentous/extensor mechanism) on the contralateral knee
• Contralateral knee pain \& symptoms - defined as a VAS of \>4/10 at initial pre-op visit
• Contralateral knee OA quantified as: Kellgren and Lawrence grade \>2-4
⁃ Assessed by PI (AK) who will not be contributing any patients to the study through examination of blinded knee radiographs (3 views: AP/lateral/Sunrise)
• Patient is able to read and understand English and provide informed consent to participation in the study