Mechanical and Molecular Determinants of Cartilage Response to Exercise
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This pilot randomize trial tests the feasibility of administering two different exercise programs in people with knee osteoarthritis. One group receives the exercise program administered as usual, and the other group received the exercise program with resting intervals.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 45
Maximum Age: 79
Healthy Volunteers: f
View:
• Age between 45 and 79 yo.
• Clinical diagnosis of primary, early to moderate stage knee osteoarthritis.
• BMI range \< 35 kg/m2.
• Sedentary lifestyle
• Knee joint is the most painful joint in the body.
• Ability to speak and understand English.
• Willingness to comply with all study procedures and be available for the duration of the study.
Locations
United States
Pennsylvania
University of Pittsburgh
RECRUITING
Pittsburgh
Contact Information
Primary
Gaupp
awg26@pitt.edu
412-383-0742
Time Frame
Start Date: 2024-12-04
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 20
Treatments
Experimental: Exercise With Rest
Participants in this arm exercise 3 times a week for 12 weeks. Exercise program consists of warm-up, strengthening exercises of the lower major extremity muscle groups, and aerobic training using a treadmill. These sessions include two 45 minute rest periods between exercises and take about two and a half hours.
Active_comparator: Exercise Without Rest
Exercise without Rest
Related Therapeutic Areas
Sponsors
Leads: University of Pittsburgh
Collaborators: Carnegie Mellon University