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Effects of Diagonal Proprioceptive Neuromuscular Facilitation Patterns on Pain and Functional Outcomes in Patients With Knee Osteoarthritis

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

A randomized controlled trial will be conducted at the Department of Physiotherapy, Dr. Ziauddin Hospital and Al-Rayaz Hospital, Karachi, Pakistan. A total of 150 patients diagnosed with knee osteoarthritis, aged between 40-60 years, will be recruited through a non-probability purposive sampling technique. Written informed consent will be obtained from all eligible participants prior to enrollment. The participants will be randomly allocated by the help of computer generated randomization sheet, into two groups i.e. experimental and the control group, with 75 participants in each group. Group A (experimental group) will receive diagonal proprioceptive neuromuscular facilitation (PNF) pattern exercises, while Group B (control group) will receive conventional strength training exercises. Heat therapy will be administered to both groups. All participants will be assessed using a standardized assessment form. Outcome measures will include pain intensity, knee range of motion, functional disability, hamstring flexibility, dynamic balance, and fatigue level. A single blinded assessor will assess all participants at baseline and at post intervention. Treatment sessions will be given thrice a week on alternate days for 6 weeks.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 60
Healthy Volunteers: f
View:

• Both male and females with an age range between 40-60 years.

• Patients diagnosed with unilateral or bilateral Knee OA.

• Grade-II or grade-III on kellgren and Lawrence classification.

• Patients having pain intensity more than 3.4 cm on VAS as minimum cut off value.

• Duration of knee OA more than 3 months (chronic).

Locations
Other Locations
Pakistan
Al-Rayaz Hospital
RECRUITING
Karachi
Dr. Ziauddin Hospital
RECRUITING
Karachi
Contact Information
Primary
Rabia Hassan, MSAPT
rabiahassan096@gmail.com
+923345448859
Backup
Basit Ansari, PhD
basitansari@hotmail.com
+923222279221
Time Frame
Start Date: 2026-02-07
Estimated Completion Date: 2027-02-22
Participants
Target number of participants: 150
Treatments
Experimental: Diagonal Proprioceptive Neuromuscular Facilitation (PNF) Pattern Exercises + Heat Therapy.
This arm will receive PNF pattern exercises using Diagonal 1 and Diagonal 2 Lower Limb Patterns of PNF and the heat therapy
Active_comparator: Conventional Strength Training Exercises + Heat Therapy
This arm will receive evidence based treatment of Quadripceps and Hip Abductor Strengthening exercises and the heat therapy.
Related Therapeutic Areas
Sponsors
Leads: University of Karachi

This content was sourced from clinicaltrials.gov

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