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Rehabilitation of Knee Osteoarthritis by High Intensity Laser Therapy vs Classical Modalities

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to compare the effectiveness and safety of High-Intensity Laser Therapy (HILT) with conventional physical therapy treatments in patients with knee osteoarthritis. Knee osteoarthritis is a common condition, especially in older adults, causing pain, stiffness, reduced movement, and difficulty performing daily activities. Current treatments focus on reducing pain and improving joint function. In this study, 100 patients with knee osteoarthritis will be divided into two groups. One group will receive HILT combined with therapeutic exercises, while the other group will receive conventional physical therapy modalities along with the same exercises. The treatment outcomes will be evaluated over time. The main outcomes include pain reduction (measured by pain scales such as WOMAC and VAS), improvement in joint function, and structural changes in the knee assessed by MRI. In addition, laboratory tests will be used to measure inflammation, cartilage health markers, and oxidative stress before and after treatment. The goal is to determine whether HILT provides better pain relief, improves joint function, and is safe compared to standard therapy. The results may help improve rehabilitation strategies for patients with knee osteoarthritis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 60
Healthy Volunteers: t
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• Diagnosis of Knee Osteoarthritis: Patients must have a clinical and radiographic diagnosis of knee OA according to the American College of Rheumatology (ACR) criteria, including evidence of joint space narrowing, osteophyte formation, and other degenerative changes observed on X-rays or MRI.

⁃ Age: Adults aged between 40 and 75 years. Willingness to Participate: Participants must provide informed consent and be willing to adhere to the study protocol, including attending all treatment sessions and follow-up assessments.

⁃ Kellgren-Lawrence Grade: Patients with knee OA grades 1-3 (mild to moderate OA).

Locations
Other Locations
Iraq
Aylan Center
RECRUITING
Erbil
Contact Information
Primary
Mahdi Qadir, PhD
mahdiqader@epu.edu.iq
+9647504631542
Backup
Shukur Smail, PhD
shukur.smail@gmail.com
07504631542
Time Frame
Start Date: 2026-04-20
Estimated Completion Date: 2027-01-20
Participants
Target number of participants: 100
Treatments
Experimental: Experimental Group (HILT)
Patients will receive High-Intensity Laser Therapy (HILT) combined with a standardized therapeutic exercise program. HILT parameters include four-wavelength beam, continuous/modulating frequencies, and SuperPulse mode for deep penetration.
Active_comparator: Classical Modalities
Patients will receive classical physical modalities (such as therapeutic ultrasound or TENS, as per standard local practice) combined with the same standardized therapeutic exercise program.
Related Therapeutic Areas
Sponsors
Leads: Erbil Polytechnic University

This content was sourced from clinicaltrials.gov