Prediction of Immune Status on the Efficacy of Metformin in the Treatment of Polycystic Ovary Syndrome
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
In this study, the investigators will include PCOS patients who meet the trial criteria, introduce participants to the content of this study, and invite participants to participate. The immune function of peripheral blood samples of PCOS patients was detected by flow cytometry. Participants were further treated with metformin for 6 months and followed up after the intervention. The objective of this study was to investigate immune markers related to the efficacy of metformin in PCOS patients and to predict the efficacy of metformin in PCOS patients using immune function.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:
• aged 18-45 years
• Diagnosis of PCOS with the Rotterdam diagnosis criteria (2003)
Locations
Other Locations
China
Department of Endocrinology, Shanghai Tenth People's Hospital
RECRUITING
Shanghai
Contact Information
Primary
Manna Zhang, doctor
mannazhang@126.com
+8613774448495
Time Frame
Start Date: 2024-03-16
Estimated Completion Date: 2026-07-01
Participants
Target number of participants: 100
Treatments
Experimental: Metformin therapy
Metformin intervention, 1000mg daily for the first week, 1500mg daily starting in the second week until six months of treatment.
Related Therapeutic Areas
Sponsors
Leads: Shanghai 10th People's Hospital