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Incidence,Perioperative Risk Factors and Prognosis Associated With Laryngopharyngea Injury After Endotracheal Intubation Under General Anesthesia:A Retrospective Study

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

This study retrospectively analyzed patients who underwent tracheal intubation under general anesthesia at the First Affiliated Hospital of Zhejiang University School of Medicine between October 1, 2015, and September 30, 2025, with a focus on issues related to postoperativelaryngopharyngeal complaints. Patients requiring otolaryngological consultation due to postoperative laryngopharyngeal complaints were identified via the case consultation system. Relevant patient data were collected through the Medison Anesthesia Information Management System and electronic medical record system, and telephone follow-up was conducted to assess patient prognosis. The primary outcome measures were the risk factors of postoperative hoarseness, while the secondary outcome measures included the incidence of postoperative hoarseness, the severity of vocal fold injury and its related risk factors. Additionally, the prognosis of patients and its related risk factors were evaluated. This study aims to reduce the incidence of perioperative laryngopharyngeal injury and provide a reference for the optimization of perioperative anesthetic regimens.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Patients who underwent general anesthesia with tracheal intubation at the First Affiliated Hospital of Zhejiang University School of Medicine between October 2015 and September 2025

• Patients who required otolaryngological consultation due to laryngopharyngeal complaints (including hoarseness, sore throat, cough, choking on drinking water, etc.) postoperatively

• The surgical type was non-otolaryngological surgery

Locations
Other Locations
China
he First Affiliated Hospital, Zhejiang University School of Medicine
COMPLETED
Hangzhou
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING
Hangzhou
Contact Information
Primary
Diansan Su
diansansu@yahoo.com
+8618616514088
Time Frame
Start Date: 2025-11-01
Estimated Completion Date: 2026-12-25
Participants
Target number of participants: 1200
Treatments
hoarseness
We collected perioperative clinical data from the cohort, analyzed the associated risk factors for the occurrence of relevant symptoms, and investigated the prognosis.
Sponsors
Leads: Zhejiang University

This content was sourced from clinicaltrials.gov