Clinical Onboard Utilization of Image Guided Radiation Therapy With Magnetic Resonance (CONFIRM): A Master Protocol
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Radiation
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Participants must have histologically or cytologically confirmed malignancy requiring radiation
• Age 18 years of older
• ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A)
• Ability to understand and the willingness to sign a written informed consent document.
• Any further criteria listed in the specific disease site cohort
Locations
United States
Massachusetts
Brigham & Women's Hospital
RECRUITING
Boston
Dana Farber Cancer Institute
RECRUITING
Boston
Contact Information
Primary
Raymond Mak, MD
rmak@partners.org
6177328651
Time Frame
Start Date: 2021-05-01
Estimated Completion Date: 2029-06-18
Participants
Target number of participants: 70
Treatments
Experimental: Phase I - Gastric Cancer
The research study procedures include:~* Screening for eligibility~* Study treatment including evaluations~* MR-image guided radiation will be administered per disease site standards.~* Follow up visits~* Questionnaires
Experimental: Phase I - Breast Cancer
The research study procedures include:~* Screening for eligibility~* Study treatment including evaluations~* MR-image guided radiation will be administered per disease site standards.~* Follow up visits~* Questionnaires
Experimental: Phase I - Mantle Cell Lymphoma
The research study procedures include:~* Screening for eligibility~* Study treatment including evaluations~* MR-image guided radiation will be administered per disease site standards.~* Follow up visits~* Questionnaires
Experimental: Phase I - Larynx
The research study procedures include:~* Screening for eligibility~* Study treatment including evaluations~* MR-image guided radiation will be administered per disease site standards.~* Follow up visits~* Questionnaires
Experimental: Phase I - Bladder
The research study procedures include:~* Screening for eligibility~* Study treatment including evaluations~* MR-image guided radiation will be administered per disease site standards.~* Follow up visits~* Questionnaires
Authors
Related Therapeutic Areas
Sponsors
Leads: Brigham and Women's Hospital