Assessment of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy on Pain Reduction and Improvement of Quality of Life in Patients With Chemotherapy Induced Peripheral Neuropathy
The goal of this observational study is to learn about the effectiveness of closed-loop spinal cord stimulation (CL-SCS) therapy for treatment of painful chemotherapy induced peripheral neuropathy. The closed-loop SCS (CL-SCS) system stimulates the nerves in the spinal cord, measures their responses and automatically adjust the stimulation level accordingly in real time for each delivered pulse.
• Subject is deemed a suitable candidate for SCS implantation and has been routinely scheduled to undergo an SCS implantation with the Evoke SCS System.
• Subject has a minimum of leg or arm pain intensity of 5/10 on the numeric rating scale (NRS) at baseline due to CIPN.
• Patients with CIPN following chemotherapy and at least 6 months post-treatment
• CIPN symptoms for a minimum duration of 3 months.
• Patient deemed to be in remission per discretion of treating oncologist
• No existing contraindications for SCS
• Subject is ≥ 18 years old.
• Subject is not pregnant or nursing.
• Subject is willing and capable of giving informed consent.
• No satisfactory treatment effect with anti-neuropathic medication or intolerable side-effects
• No satisfactory treatment effect with minimal invasive pain treatments (including ketamine or lidocaine infusion therapy)