Polycystic Kidney Disease Latest Advances

Endoplasmic reticulum-mitochondrion disconnection promotes metabolic reprogramming and cystogenesis in polycystic kidney disease.

Journal: bioRxiv : the preprint server for biology

Published: December 08, 2025

Ciliary ARLs drive renal cystogenesis.

Journal: bioRxiv : the preprint server for biology

Published: December 03, 2025

Discovery of Non-benzoazacyclic V2R Antagonists for the Treatment of Autosomal Dominant Polycystic Kidney Disease.

Journal: Journal of medicinal chemistry

Published: November 29, 2025

Real-world evidence for using urine osmolality as a practical tool in tolvaptan dose optimization in patients with ADPKD.

Journal: Clinical nephrology

Published: November 27, 2025

Disruption of a six-nucleotide miRNA motif improves PKD1 dosage and ameliorates polycystic kidney disease.

Journal: bioRxiv : the preprint server for biology

Published: November 24, 2025

Extra-ciliary role for polycystins in regulation of Ezrin and renal tubular morphology.

Journal: bioRxiv : the preprint server for biology

Published: November 24, 2025

Molecular Diagnosis and Identification of a Novel Pathogenic Variant in Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Case in Full Bloom.

Journal: Cureus

Published: November 16, 2025

Hyponatraemia and cancer.

Journal: Best practice & research. Clinical endocrinology & metabolism

Published: November 13, 2025

Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 13, 2025

A Case of TSC2/PKD1 Contiguous Gene Deletion Syndrome With Proven Kidney Pathology.

Journal: Kidney medicine

Published: November 10, 2025

Kidney stones and autosomal dominant polycystic kidney disease: a state-of-the-art review.

Journal: Renal failure

Published: November 10, 2025

Qualitative Analysis and Comparison of Externally Led Patient-Focused Drug Development Concepts for Autosomal Recessive Polycystic Kidney Disease Against SONG Initiatives.

Journal: Kidney medicine

Published: November 10, 2025

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Endoplasmic reticulum-mitochondrion disconnection promotes metabolic reprogramming and cystogenesis in polycystic kidney disease.

Endoplasmic reticulum-mitochondrion disconnection promotes metabolic reprogramming and cystogenesis in polycystic kidney disease.

Ciliary ARLs drive renal cystogenesis.

Ciliary ARLs drive renal cystogenesis.

Discovery of Non-benzoazacyclic V2R Antagonists for the Treatment of Autosomal Dominant Polycystic Kidney Disease.

Discovery of Non-benzoazacyclic V2R Antagonists for the Treatment of Autosomal Dominant Polycystic Kidney Disease.

Real-world evidence for using urine osmolality as a practical tool in tolvaptan dose optimization in patients with ADPKD.

Real-world evidence for using urine osmolality as a practical tool in tolvaptan dose optimization in patients with ADPKD.

Disruption of a six-nucleotide miRNA motif improves PKD1 dosage and ameliorates polycystic kidney disease.

Disruption of a six-nucleotide miRNA motif improves PKD1 dosage and ameliorates polycystic kidney disease.

Extra-ciliary role for polycystins in regulation of Ezrin and renal tubular morphology.

Extra-ciliary role for polycystins in regulation of Ezrin and renal tubular morphology.

Molecular Diagnosis and Identification of a Novel Pathogenic Variant in Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Case in Full Bloom.

Molecular Diagnosis and Identification of a Novel Pathogenic Variant in Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Case in Full Bloom.

Hyponatraemia and cancer.

Hyponatraemia and cancer.

Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease.

Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease.

A Case of TSC2/PKD1 Contiguous Gene Deletion Syndrome With Proven Kidney Pathology.

A Case of TSC2/PKD1 Contiguous Gene Deletion Syndrome With Proven Kidney Pathology.

Kidney stones and autosomal dominant polycystic kidney disease: a state-of-the-art review.

Kidney stones and autosomal dominant polycystic kidney disease: a state-of-the-art review.

Qualitative Analysis and Comparison of Externally Led Patient-Focused Drug Development Concepts for Autosomal Recessive Polycystic Kidney Disease Against SONG Initiatives.

Qualitative Analysis and Comparison of Externally Led Patient-Focused Drug Development Concepts for Autosomal Recessive Polycystic Kidney Disease Against SONG Initiatives.