Effect of NMN (Nicotinamide Mononucleotide) Intervention on Patients With Diminished Ovarian Reserve (Including Premature Ovarian Insufficiency)
Status: Recruiting
Location: See location...
Intervention Type: Other, Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of the study is to understand the effect of nicotinamide mononucleotide (NMN) on patients with diminished ovarian reserve (including premature ovarian insufficiency).
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 20
Maximum Age: 40
Healthy Volunteers: f
View:
• Individuals who are 20 to 40 years old.
• The concentrations of anti-Mullerian hormone \< 1.1 ng/ml, the values of antral follicle count range from less than 5 to less than 7 and two recordings of serum concentrations of day-3 follicle-stimulating hormone (FSH) ≥10 IU/L.
• Individuals who can insist on continuous monitoring in the outpatient clinic.
• Individuals who are not participating in other research projects currently or 3 months before the intervention.
Locations
Other Locations
China
Peking University Third Hospital
RECRUITING
Beijing
Time Frame
Start Date: 2022-07-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 200
Treatments
Experimental: NMN intervention
3 months of NMN
Placebo_comparator: Placebo
3 months of NMN-free placebo
Related Therapeutic Areas
Sponsors
Leads: Peking University Third Hospital