Investigating Reactivation of Ovarian Function Following Autologous PRP Intra-ovarian Infusion in POI Patients
Who is this study for? Adult women with premature ovarian failure
What treatments are being studied? Autologous Platelet Rich Plasma
Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY
Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve patients' hormonal profile in patients presenting with POI.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 25
Maximum Age: 39
Healthy Volunteers: t
View:
• Age \< 40 years, presenting with amenorrhea or menstrual cycle irregularities for at least four months, and elevated FSH levels \>25 IU/L recorded on two occasions \>4 weeks apart
• Normal Karyotype: 46, XX
• Discontinuation of any complementary/adjuvant treatment including hormone replacement, acupuncture, and botanotherapy, for at least three months prior to recruitment.
• Willing to comply with study requirements
Locations
Other Locations
Greece
Genesis AC
RECRUITING
Athens
Contact Information
Primary
Mara Simopoulou, PhD
marasimopoulou@hotmail.com
+306979234100
Backup
Agni Pantou, MD, PhD Candidate
Time Frame
Start Date: 2019-07-30
Estimated Completion Date: 2026-07-30
Participants
Target number of participants: 100
Treatments
Experimental: Participants receiving PRP treatment
Women presenting with POI, 25-39 years of age, treated with autologous PRP intra ovarian infusion
Placebo_comparator: Participants receiving Platelet Free Plasma (PFP) treatment
Women presenting with POI, 25-39 years of age, treated with autologous PFP intra ovarian infusion
Related Therapeutic Areas
Sponsors
Collaborators: National and Kapodistrian University of Athens
Leads: Genesis Athens Clinic