Evaluation of the Effect of Respiratory Physiotherapy by Mechanical In-exsufflator on Respiratory Function in Patients with Amyotrophic Lateral Sclerosis: a Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The study aims to evaluate the effect of mechanical insufflator-exsufflator on the respiratory functions of Amyotrophic Lateral Sclerosis (ALS) patients evaluated via peak expiratory flow on cough (PEFC) measurements. The evolution of their PEFC is monitored to see if the curative management can have a positive impact on the latter.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:

• Confirmed ALS categorized as probable or certain according to the revised Awaji-Shima criteria \[27\].

• ALS of spinal, bulbar or respiratory forms

• Peak Flow measure between 160 and 255 L/min (recommendation of MIE in case of congestion, with the possibility of daily sessions)

• Patient who has not benefited from treatment by MIE in the past year (less than 10 sessions in total)

• Patient able to use the MIE and perform the collection, or having a caregiver able to help

• Patient receiving physiotherapist treatment greater than or equal to twice a week

Locations
Other Locations
France
SLA Center - Purpan University Hospital Toulouse, FRANCE
RECRUITING
Toulouse
Contact Information
Primary
Thierry LAGARDE, PT
lagarde.t@chu-toulouse.fr
+33561775570
Backup
Floriane LLORENS
llorens.fl@chu-toulouse.fr
Time Frame
Start Date: 2023-08-29
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 36
Treatments
Experimental: Mechanical In-Exsufflator treatment
Sponsors
Leads: University Hospital, Toulouse

This content was sourced from clinicaltrials.gov