Primary Lateral Sclerosis Latest Advances

Precision Channel Engineering of Nanotube-Embedded Organic Electrochemical Transistors for Ultrasensitive Neurofilament Light Chain Detection.

Journal: ACS applied bio materials

Published: January 23, 2026

Dual-targeting snRNA gene therapy rescues STMN2 and UNC13A splicing in TDP-43 proteinopathies.

Journal: bioRxiv : the preprint server for biology

Published: January 23, 2026

Reduced osteogenic factors and early osteoblast senescence in SOD1(G93A) ALS mouse model.

Journal: JCI insight

Published: January 22, 2026

Advancing treatment of spinal muscular atrophy through inhibition of the myostatin signaling pathway.

Journal: Expert review of neurotherapeutics

Published: January 22, 2026

The preclinical discovery and development of edaravone for the treatment of amyotrophic lateral sclerosis: what lessons have we learnt?

Journal: Expert opinion on drug discovery

Published: January 22, 2026

Strengthening clinical capacity in spinal muscular atrophy: Developing and implementing training on clinical outcome assessments.

Journal: Journal of neuromuscular diseases

Published: January 21, 2026

Addendum to the 2023 clinical practice guidelines for amyotrophic lateral sclerosis in Japan: approval and integration of novel disease-modifying therapies.

Journal: Rinsho shinkeigaku = Clinical neurology

Published: January 21, 2026

Minimum important slowing of disease progression as determined by the ALS functional rating scale - a survey of patient expectations toward disease-modifying drugs in ALS.

Journal: Amyotrophic lateral sclerosis & frontotemporal degeneration

Published: January 20, 2026

Computational Exploration of the Molecular Mechanism of Epigallocatechin Gallate against TDP-43 Aggregation.

Journal: Journal of chemical information and modeling

Published: January 20, 2026

Long-Term Exposure to Air Pollution and Risk and Prognosis of Motor Neuron Disease.

Journal: JAMA neurology

Published: January 20, 2026

Emerging Alzheimer's therapies: clinical efficacy versus economic feasibility.

Journal: Neurodegenerative disease management

Published: January 19, 2026

Scoliosis correction in spinal muscular atrophy : the influence of genetic severity, functional level, and disease-modifying agents on postoperative outcomes.

Journal: Bone & joint open

Published: January 16, 2026