Electrical Impedance Myography: Natural History Studies in Neuromuscular Disorders and Healthy Volunteers

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Background: \- Electrical impedance myography (EIM) is a new technique being studied to see if it is helpful in evaluating muscle disorders and nerve disorders. EIM looks at how a mild, painless electrical current travels through muscles. Researchers want to gain experience in using the EIM device. They will collect information on the results of using it on people with and without nerve and muscle diseases, and compare that with information from other standard tests. First, they will test the device on healthy people. Then they will test people with a variety of neuromuscular diseases. Because the test is noninvasive and not painful, researchers will test both children and adults.

Objectives: \- To gain experience using the EIM muscle testing device.

Eligibility: * Healthy volunteers at least 2 years old. * Individuals at least 2 years old who have neuromuscular disease.

Design: * Participants will be screened with a medical history and physical exam. * Participants will have one 2-3 hour clinic visit. Researchers may request follow-up visits. * Participants will be tested with the EIM device. The device and small electrodes will be placed on their skin. An electric current will pass through the device, but the participants will not feel this. * Participants may have an ultrasound test. A gel will be put on their skin, and a device will be moved over the skin. * Participants may have a nerve test. Electrodes will be placed on their skin, and they will feel a small shock. * Participants may have a test where a thin needle is inserted in their muscle.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 110
Healthy Volunteers: t
View:

• Suspected motor neuron disease or

• Suspected myopathy or

• Suspected neuropathy or

• Suspected movement disorders that impair intracortical processes

• Age of 2 years or older

• Ability of subject to sign a written informed consent document.

⁃ NIH EMPLOYEES:

⁃ NIH employees and staff may participate, however EMG Section, OCD, NINDS, employees may not participate.

Locations
United States
Maryland
National Institutes of Health Clinical Center
RECRUITING
Bethesda
Contact Information
Primary
Candida C Silva
candida.silva@nih.gov
(301) 496-7428
Backup
Tanya J Lehky, M.D.
lehkyt@ninds.nih.gov
(301) 496-7428
Time Frame
Start Date: 2013-06-20
Estimated Completion Date: 2026-06-01
Participants
Target number of participants: 275
Treatments
Experimental: 1/All Subjects
Healthy Volunteers and patients
Related Therapeutic Areas
Sponsors
Leads: National Institute of Neurological Disorders and Stroke (NINDS)

This content was sourced from clinicaltrials.gov