Prospective Observational Study for the Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases
This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.
• diagnosis of probable or possible multiple system atrophy according to current consensus criteria (Gilman et al. 2008) or
• diagnosis of probable or possible PSP according to the the Movement Disorders Society (MDS) diagnostic criteria (Höglinger et al. 2017) or
• diagnosis of Parkinson's disease according to the MDS diagnostic criteria (Postuma et al 2015)
• Hoehn and Yahr Stage within the range of I-V or
• diagnosis of motor neurone disease or
• diagnosis of a neurodegenerative disease other than specified above
⁃ AND underwent laryngopharyngeal assessment according to the systematic task protocol during FEES (Warnecke et al. 2019).