Psoriatic Arthritis
Symptoms, Doctors, Treatments, Advances & More

Learn About Psoriatic Arthritis

View Main Condition: Arthritis

What is the definition of Psoriatic Arthritis?

Psoriatic arthritis is a joint problem (arthritis) that often occurs with a skin condition called psoriasis.

What are the alternative names for Psoriatic Arthritis?

Arthritis - psoriatic; Psoriasis - psoriatic arthritis; Spondyloarthritis - psoriatic arthritis; PsA

What are the causes of Psoriatic Arthritis?

Psoriasis is a common skin problem that causes red patches on the skin. It is an ongoing (chronic) inflammatory condition. Psoriatic arthritis occurs in 7% to 42% of people with psoriasis. Nail psoriasis is linked to psoriatic arthritis.

In most cases, psoriasis comes before the arthritis. In a few people, the arthritis comes before the skin disease. However, having severe, wide-spread psoriasis appears to increase the chance of getting psoriatic arthritis.

The cause of psoriatic arthritis is not known. Genes, immune system, and environmental factors may play a role. It is likely that the skin and joint diseases have similar causes. However, they may not occur together.

What are the symptoms of Psoriatic Arthritis?

The arthritis may be mild and involve only a few joints. The joints at the end of the fingers or toes may be more affected. Psoriatic arthritis can cause arthritis only on one side of the body or both sides of the body.

In some people, the disease may be severe and affect many joints, including the spine. Symptoms in the spine include stiffness and pain. They most often occur in the lower spine and sacrum.

Some people with psoriatic arthritis may have inflammation of the eyes.

Most of the time, people with psoriatic arthritis have the skin and nail changes of psoriasis. Often, the skin gets worse at the same time as the arthritis.

Tendons may become inflamed with psoriatic arthritis. Examples include the Achilles tendon, the plantar fascia, and the tendon sheath in the hand.

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What are the current treatments for Psoriatic Arthritis?

Your provider may suggest nonsteroidal anti-inflammatory drugs (NSAIDs) to reduce pain and swelling of the joints.

Arthritis that does not improve with NSAIDs may need to be treated with medicines called disease-modifying antirheumatic drugs (DMARDs). These include:

  • Methotrexate
  • Leflunomide
  • Sulfasalazine

Apremilast is another medicine used for the treatment of psoriatic arthritis.

Multiple injectable biologic medicines are effective for progressive psoriatic arthritis that is not controlled with DMARDs. These medicines block proteins involved in the inflammation process. They are often helpful for both the skin disease and the joint disease of psoriatic arthritis.

Additionally, there are two JAK-inhibitors that are approved for psoriatic arthritis: Tofacitinib and Upadacitinib. These medications are given orally.

Very painful joints may be treated with steroid injections. These are used when only one or a few joints are involved. Most experts do not recommend oral corticosteroids for psoriatic arthritis. Their use may worsen psoriasis and interfere with the effect of other medicines.

In rare cases, surgery may be needed to repair or replace damaged joints.

People with inflammation of the eye should see an ophthalmologist.

Your provider may suggest a mix of rest and exercise. Physical therapy may help increase joint movement. You may also use heat and cold therapy.

Who are the top Psoriatic Arthritis Local Doctors?
Elite in Psoriatic Arthritis
Internal Medicine | Rheumatology
Elite in Psoriatic Arthritis
Internal Medicine | Rheumatology

Reading Hospital

420 South 5th Avenue, 
West Reading, PA 
Languages Spoken:
English

. Dr. Chakravarty is rated as an Elite provider by MediFind in the treatment of Psoriatic Arthritis. He is also highly rated in 4 other conditions, according to our data. His clinical expertise encompasses Psoriatic Arthritis, Psoriasis, Arthritis, and Ankylosing Spondylitis. Dr. Chakravarty is board certified in American Board Of Internal Medicine.

Elite in Psoriatic Arthritis
Rheumatology
Elite in Psoriatic Arthritis
Rheumatology

Seattle Rheumatology Associates

601 Broadway, 
Seattle, WA 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Dr. Mease graduated from Stanford University receiving his Medical Doctorate. He specializes in internal medicine and rheumatology. Dr. Mease is a practicing physician at Seattle Rheumatology Associates, Swedish Cherry Hill, and Swedish First Hill. Dr. Mease is rated as an Elite provider by MediFind in the treatment of Psoriatic Arthritis. He is also highly rated in 10 other conditions, according to our data. His clinical expertise encompasses Psoriatic Arthritis, Arthritis, Psoriasis, and Axial Spondyloarthritis (AxSpA). Dr. Mease is board certified in American Board Of Internal Medicine. Dr. Mease is currently accepting new patients.

 
 
 
 
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Elite in Psoriatic Arthritis
Rheumatology
Elite in Psoriatic Arthritis
Rheumatology

Johns Hopkins Bayview Medical Center

Baltimore, MD 
Languages Spoken:
English, Romanian
Offers Telehealth

Dr. Ana-Maria Orbai is an Associate Professor of Medicine in the Division of Rheumatology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include rheumatology and psoriatic arthritis. Dr. Orbai earned her M.D. from the Iuliu Hatieganu School of Medicine and Pharmacy, Cluj-Napoca, in Romania. She completed internship and residency training in internal medicine at the Johns Hopkins University-Sinai Hospital program. Subsequently, Dr. Orbai completed her post-doctoral fellowship training in rheumatology at Johns Hopkins. During her fellowship she earned her Master in Health Sciences degree in Clinical Investigation at the Johns Hopkins Bloomberg School of Public Health. Dr. Orbai directs the Psoriatic Arthritis Program in the Johns Hopkins Arthritis Center. Her clinical focus is psoriatic arthritis and spodyloarthritis. Dr. Orbai's research aims to understand psoriatic disease subtypes and improve treatment strategies for people with psoriatic arthritis. Dr. Orbai was awarded a Rheumatology Research Foundation Scientist Development award in 2014 and a Jerome L Greene Foundation Scholar award in 2018. Dr. Orbai is rated as an Elite provider by MediFind in the treatment of Psoriatic Arthritis. She is also highly rated in 6 other conditions, according to our data. Her clinical expertise encompasses Psoriatic Arthritis, Psoriasis, Arthritis, and Rheumatoid Arthritis (RA). Dr. Orbai is board certified in American Board Of Internal Medicine.

What is the outlook (prognosis) for Psoriatic Arthritis?

The disease is sometimes mild and affects only a few joints. However, in many people with psoriatic arthritis damage to joints occurs within the first several years. In some people, very bad arthritis may cause deformities in the hands, feet, and spine.

Most people with psoriatic arthritis who do not improve with NSAIDs should see a rheumatologist, a specialist in arthritis, along with a dermatologist for the psoriasis.

Early treatment can ease pain and prevent joint damage, even in very bad cases.

When should I contact a medical professional for Psoriatic Arthritis?

Contact your provider if you develop symptoms of arthritis along with psoriasis.

What are the latest Psoriatic Arthritis Clinical Trials?
Comprehensive Characterization of Immune Response Induced by Adjuvanted Glycoprotein E (gE)-Based Recombinant VAccine Zoster in Vulnerable Population Receiving ImmunOmodulaNt Therapies

Summary: Varicella-zoster virus (VZV) is one of the eight herpesviruses that infect humans by manifesting as varicella. After primary infection VZV remains latent for life. In 30% of individuals the virus reactivates causing a secondary infection, herpes zoster (HZ). The most common complication of HZ is post-herpetic neuralgia (PHN) and, in severe cases, disseminated infection and death. The incidence of ...

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Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine (Butantan-DV) in Patients With Autoimmune Rheumatic Diseases Living in Dengue-Endemic Areas

Summary: The goal of this clinical trial is to evaluate whether the live attenuated tetravalent Butantan-Dengue vaccine (Butantan-DV) is safe and capable of inducing an immune response in patients aged 12 to 59 years with autoimmune rheumatic diseases (ARDs) who are clinically stable and under low-grade or no immunosuppression, as well as in healthy volunteers matched by sex and age. The main questions it ...

Who are the sources who wrote this article ?

Published Date: January 28, 2025
Published By: Diane M. Horowitz, MD, Rheumatology and Internal Medicine, Northwell Health, Great Neck, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Gossec L, Kerschbaumer A, Ferreira RJO, et al. EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2023 update Ann Rheum Dis 2024;83:706-719. PMID: 38499325 pubmed.ncbi.nlm.nih.gov/38499325/.

Haberman RH, Scher JU. Psoriatic arthritis. In: Firestein GS, McInnes IB, Koretzky GA, Mikuls TR, Neogi T, O’Dell JR, eds. Firestein & Kelley's Textbook of Rheumatology. 12th ed. Philadelphia, PA: Elsevier; 2025:chap 78.

Inman RD, Rahman P. Spondyloarthritis. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 244.

Veale DJ, Orr C. Management of psoriatic arthritis. In: Hochberg MC, Gravallese EM, Smolen JS, van der Hejjde D, Weinblatt ME, Weisman MH, eds. Rheumatology. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 131.