Association of Anti-factor Xa Activity With Venous Thromboembolism in Critically Ill Patients: a Prospective Multicentre Cohort Study

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

The goal of this observational study is to analyse the association between anti-factor Xa activity (antiXa) and the occurence of venous thromboembolism (VTE; either deep vein thrombosis and/or pulmonary embolism) in critically ill patients who are admitted to an intensive care unit. The main questions it aims to answer are: * What is the association between antiXa and VTE? * What is the association between antiXa and symptomatic, respectively incidental, VTE? * How is pharmacological anticoagulation with enoxaparin related to measured antiXa? * What is the association between antiXa and bleeding complications. * What is the incidence of venous thromboembolism in patients treated at an intensive care unit? * How is the occurence of VTE related to patient-centred outcomes such as mortality, quality of life, length of stay and days outside of the intensive care unit/hospital.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age over 18 years at the time of intensive care unit admission

• Admission to a participating intensive care unit within the last 24 hours

• Expected discharge is later than 48 hours after enrolment

Locations
Other Locations
Austria
Department of Internal Medicine, Medical University of Graz
RECRUITING
Graz
Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna
RECRUITING
Vienna
Contact Information
Primary
Christoph Dibiasi, MD
christoph.dibiasi@meduniwien.ac.at
0043 1 40400
Time Frame
Start Date: 2024-05-04
Estimated Completion Date: 2027-08
Participants
Target number of participants: 1300
Treatments
Intensive care unit patients
Patients who are admitted to an participating intensive care unit who do not receive therapeutic anticoagulation.
Sponsors
Leads: Medical University of Vienna

This content was sourced from clinicaltrials.gov

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