Pure Red Cell Aplasia
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Pure Red Cell Aplasia Overview

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Learn About Pure Red Cell Aplasia

What is the definition of Pure Red Cell Aplasia?
Pure red cell aplasia (PRCA) is a rare condition that affects the bone marrow. Bone marrow contains stem cells which develop into the red blood cells that carry oxygen through the body, the white blood cells that fight infections, and the platelets that help with blood clotting. In people with PRCA, the bone marrow makes a reduced number of red blood cells (called anemia). As a result, affected people may experience fatigue, lethargy, and pale skin. PRCA has many different causes. A rare congenital form of PRCA, called Diamond Blackfan syndrome, is an inherited condition that is also associated with other physical abnormalities. PRCA can also be due to certain medications, infections, pregnancy, renal failure, and conditions such as thymomas, autoimmune disease (such as systemic lupus erythematosus), cancers of the blood, and solid tumors. In many cases, the cause of the condition is unknown (idiopathic).
What are the alternative names for Pure Red Cell Aplasia?
  • Pure red cell aplasia
  • PRCA
Who are the top Pure Red Cell Aplasia Local Doctors?
Elite in Pure Red Cell Aplasia
Dr. Adrianna Vlachos
Hematology | Pediatric Hematology Oncology
Elite in Pure Red Cell Aplasia
Dr. Adrianna Vlachos
Hematology | Pediatric Hematology Oncology
Referral may be required

Johns Hopkins All Children's Outpatient Care, Tampa

12220 Bruce B Downs Boulevard, 
Tampa, FL 
727-767-4176
Languages Spoken:
English, Greek
See accepted insurances
Accepting New Patients
Offers Telehealth

Adrianna Vlachos is a Hematologist and a Pediatric Hematologist Oncology provider practicing medicine in Tampa, Florida. Dr. Vlachos is rated as an Elite provider by MediFind in the treatment of Pure Red Cell Aplasia. She is also highly rated in 15 other conditions, according to our data. Her clinical expertise encompasses Aase Syndrome, Pure Red Cell Aplasia, Aplastic Anemia, and Transient Erythroblastopenia of Childhood. Dr. Vlachos is board certified in American Board Of Pediatrics. Dr. Vlachos is currently accepting new patients.

Elite in Pure Red Cell Aplasia
Dr. Jeffrey M. Lipton
Pediatric Hematology Oncology
Elite in Pure Red Cell Aplasia
Dr. Jeffrey M. Lipton
Pediatric Hematology Oncology
Referral may be required

Northwell Health Pediatric Hematology/Oncology & Stem Cell Transplant

269-01 76th Avenue, Suite 255, 
New Hyde Park, NY 
718-470-3460
Languages Spoken:
English
See accepted insurances
Accepting New Patients

Jeffrey Lipton is a Pediatric Hematologist Oncology provider practicing medicine in New Hyde Park, New York. Dr. Lipton is rated as an Elite provider by MediFind in the treatment of Pure Red Cell Aplasia. He is also highly rated in 7 other conditions, according to our data. His clinical expertise encompasses Aase Syndrome, Pure Red Cell Aplasia, Transient Erythroblastopenia of Childhood, Aplastic Anemia, and Bone Marrow Transplant. Dr. Lipton is board certified in American Board Of Pediatrics. Dr. Lipton is currently accepting new patients.

 
 
 
 
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Elite in Pure Red Cell Aplasia
Dr. Kathleen M. Sakamoto
Hematology | Oncology
Elite in Pure Red Cell Aplasia
Dr. Kathleen M. Sakamoto
Hematology | Oncology
Referral may be required

Office

725 Welch Rd Ste 160, 
Palo Alto, CA 
650-497-8953
Languages Spoken:
English
See accepted insurances

Kathleen Sakamoto is a Hematologist and an Oncologist practicing medicine in Palo Alto, California. Dr. Sakamoto is rated as an Elite provider by MediFind in the treatment of Pure Red Cell Aplasia. She is also highly rated in 8 other conditions, according to our data. Her clinical expertise encompasses Pure Red Cell Aplasia, Aplastic Anemia, Transient Erythroblastopenia of Childhood, Acute Lymphoblastic Leukemia (ALL), and Bone Marrow Aspiration.

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What are the latest Pure Red Cell Aplasia Clinical Trials?
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study
Enrollment Status: Recruiting
Publish Date: September 08, 2026

Background: A prospective cohort of Inherited Bone Marrow Failure Syndrome (IBMFS) will provide new information regarding cancer rates and types in these disorders. Pathogenic variant(s) in IBMFS genes are relevant to carcinogenesis in sporadic cancers. Patients with IBMFS who develop cancer differ in their genetic and/or environmental features from patients with IBMFS who do not develop cancer. These cancer-...

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T-Cell Depleted, Alternative Donor Transplant in Pediatric and Adult Patients With Severe Sickle Cell Disease (SCD) and Other Transfusion-Dependent Anemias
T-Cell Depleted, Alternative Donor Transplant in Pediatric and Adult Patients With Severe Sickle Cell Disease (SCD) and Other Transfusion-Dependent Anemias
Who is this study for: Adults with sickle cell disease and other anemias
Enrollment Status: Recruiting
Publish Date: August 13, 2026
Intervention Type: Drug, Biological
Study Drugs: CD3/CD19 depleted leukocytes, CD45RA depleted leukocytes, Hydroxyurea, Rituximab, Alemtuzumab, Fludarabine, Thiotepa
Study Phase: Phase 1/Phase 2

Summary: The purpose of this study is to evaluate what effect, if any, mismatched unrelated volunteer donor and/or haploidentical related donor stem cell transplant may have on severe sickle cell disease and other transfusion dependent anemias. By using mismatched unrelated volunteer donor and/or haploidentical related donor stem cells, this study will increase the number of patients who can undergo a stem...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center