The Effect of Nicotinamide on the Clinical Outcome of Rheumatoid Arthritis Patients
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
A randomized controlled interventional study to evaluate the efficacy and safety of nicotinamide supplementation in rheumatoid arthritis patients receiving conventional synthetic disease modifying anti-rheumatic drugs.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• Adult patients (18-65 years).
• Patients with a diagnosis of established rheumatoid arthritis.
• Patients presenting with moderate to high disease activity identified as disease activity score-28 based on C-reactive protein levels (DAS-28-CRP) \>3.2.
• Receiving stable regimen of one or more conventional disease modifying antirheumatic drugs for at least the past three months.
• Patients willing to sign an informed consent.
Locations
Other Locations
Egypt
Ain Shams University Hospitals
RECRUITING
Cairo
Contact Information
Primary
Sara A. Raslan, Bachelor
Sarah.raslan@pharma.asu.edu.eg
+20 1020145174
Backup
Dalia Abdelmohsen, Professor
d_mohsen@hotmail.com
+20 100 1580007
Time Frame
Start Date: 2023-12-02
Estimated Completion Date: 2025-06
Participants
Target number of participants: 70
Treatments
Experimental: Nicotinamide group
Patients will receive nicotinamide 1000mg tablet once daily.in addition to their conventional therapy for three months.
Active_comparator: control group
Patients will receive their conventional therapy only.
Related Therapeutic Areas
Sponsors
Leads: Ain Shams University