The Frequency of Osteosarcopenia in Patients With Rheumatoid Arthritis and the Factors Affecting the Sarcopenia-osteoporosis Relationship

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

Our study is a cross-sectional study, and its aim is to compare and analyze the prevalence of sarcopenia and osteoporosis in patients with rheumatoid arthritis (RA) with a control group and to reveal the impact of sarcopenia on osteoporosis, fall risk, and fracture risk. This prospective cross-sectional study will include 100 rheumatoid arthritis patients and 100 healthy controls, matched for age and sex. Patients will be consecutively and meticulously enrolled based on inclusion and exclusion criteria. A detailed medical history and examination will be performed on the patients, and their clinical and sociodemographic characteristics will be recorded. Blood tests for RA (RF, Anti-Cyclic Citrullinated Peptide (anti-CCP), CRP, ESR) and disease activity levels (DAS28) will be recorded. The prevalence of osteosarcopenia will be assessed in both the RA and healthy control groups.These groups will be evaluated using various scales and tests (including power, performance tests) including musculoskeletal ultrasonographic measurements and clinical functional assessment tests. he sarcopenic group will be categorized based on the level of sarcopenia, according to the new ISarcoPRM criteria (non-sarcopenic, dynapenic, sarcopenic, and severe sarcopenic). Osteosarcopenia will be evaluated for both groups, and the collected data will be analyzed with primary and secondary outcomes. The analysis will explore the potential relationships between rheumatoid inflammation, sarcopenia, and osteoporosis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: t
View:

• Being diagnosed with RA according to the ACR/EULAR 2010 criteria

• Being a female or male over the age of 50

• Having the mental and physical capacity to complete the study questionnaires and tests

• Providing voluntary consent to participate in the study by signing the Informed Consent Form

Locations
Other Locations
Turkey
Konya Beyhekim Training and Research Hospital Physical Medicine and Rehabilitation Clinic
RECRUITING
Konya
Contact Information
Primary
ilhan ç KAYA
icaglar.kaya@gmail.com
09005377889686
Time Frame
Start Date: 2023-08-15
Estimated Completion Date: 2025-11-30
Participants
Target number of participants: 200
Treatments
rheumatoid arthritis grups
It includes females and males over the age of 50 who meet the RA diagnostic criteria according to the ACR/EULAR 2010 criteria.
healty control grups
It includes females and males over the age of 50 who do not meet the exclusion criteria.
Sponsors
Leads: Konya Beyhekim Training and Research Hospital

This content was sourced from clinicaltrials.gov