National Cohort on Imprinting Disorders and Their Metabolic Consequences

Status: Recruiting
Location: See all (20) locations...
Study Type: Observational
SUMMARY

The goal of this observational study is to describe the natural history of imprinting disorders (IDs) according to their metabolic profile in all patients (adults and children) affected with an ID regardless of the severity of the disease, with a molecular characterization, with a signed informed consent for all subjects, followed in one partner's center. The main questions it aims to answer are: * Can we identify common metabolic profiles for all imprinted diseases? * Which imprinting disorders have an impact on the metabolic profiles of IDs? * Which are the metabolic risks associated to IDs? * Can we use the metabolic profiles for the clinical classification and prognosis of IDs? * Are there common therapeutic approaches for all IDs?

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Patients (adults and children) affected with an ID regardless of the severity of the disease

• A confirmed diagnosis of ID (based on molecular diagnosis)

• A signed informed consent for adults or signed informed consent of parents/guardians of minors/ protected adult.

Locations
Other Locations
France
CHU d'Angers
NOT_YET_RECRUITING
Angers
Hôpital Jean Minjoz
NOT_YET_RECRUITING
Besançon
Hôpital Gabriel Montpied
NOT_YET_RECRUITING
Clermont-ferrand
Hôpital Bicêtre
RECRUITING
Le Kremlin-bicêtre
Hôpital Jeanne de Flandre
NOT_YET_RECRUITING
Lille
Hôpital de la mère et de l'enfant
NOT_YET_RECRUITING
Limoges
Hôpital Femme Mère Enfant
NOT_YET_RECRUITING
Lyon
Hôpital de la Timone
RECRUITING
Marseille
Hôpital Brabois
NOT_YET_RECRUITING
Nancy
Hôpital enfant-adolescent
NOT_YET_RECRUITING
Nantes
Hôpital Armand-Trousseau
RECRUITING
Paris
Hôpital de la Pitié-Salpêtrière
RECRUITING
Paris
Hôpital de la Pitié-Salpêtrière
RECRUITING
Paris
Hôpital Necker Enfants Malades
RECRUITING
Paris
Hôpital Robert Debré
NOT_YET_RECRUITING
Paris
Hôpital Sud
RECRUITING
Rennes
Hôpital Civil
NOT_YET_RECRUITING
Strasbourg
Hôpital des Enfants
NOT_YET_RECRUITING
Toulouse
Hôpital des Enfants
RECRUITING
Toulouse
Hôpital Bretonneau
NOT_YET_RECRUITING
Tours
Contact Information
Primary
Agnès LINGLART
agnes.linglart@aphp.fr
+33 1 45 21 78 53
Backup
Irène NETCHINE
irene.netchine@aphp.fr
Time Frame
Start Date: 2017-03-10
Estimated Completion Date: 2028-03
Participants
Target number of participants: 2000
Sponsors
Leads: Institut National de la Santé Et de la Recherche Médicale, France

This content was sourced from clinicaltrials.gov

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