Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from F8 coil or active rTMS from H coil for smoking cessation. Smoking and brain functional connectivity changes will be assessed at baseline, different stages of rTMS and/or follow-ups.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 22
Maximum Age: 65
Healthy Volunteers: f
View:

• Male and female between ages 22-65 years

• Ability to give written informed consent

• Smoking in the last one year or more and average cigarette per day ≥ 5 in the past 4 weeks

• Diagnosed with schizophrenia-spectrum disorder and Evaluation to Sign Consent (ESC) above10.

• Is currently under the care of a licensed primary care provider or mental healthcare provider (e.g., psychiatrist, psychologist, nurse practitioner, licensed clinical social worker).

• Agrees to: (a) provide written permission, as requested, to allow any and all forms of communication between the investigators and study staff and any health care provider who currently provides and/or has provided service to the subject within two years of study enrollment; and (b) provide the names and verifiable contact information (name, email and mailing address, mobile and land-line phone number, as applicable) of at least two reliable persons ≥ age 22, who reside within a 30-minute drive of the subject's residence, and whom the research staff is at liberty to contact, as deemed necessary, for the duration of study participation.

Locations
United States
Texas
The University of Texas Health Science Center, Houston
RECRUITING
Houston
Contact Information
Primary
Xiaoming Du, PhD
Xiaoming.Du@uth.tmc.edu
443-882-9717
Backup
Victoria Acosta
Victoria.Acosta@uth.tmc.edu
713-486-2740
Time Frame
Start Date: 2022-06-01
Estimated Completion Date: 2027-06-30
Participants
Target number of participants: 50
Treatments
Experimental: Study group
Participants in this group will receive active F8-coil delivered rTMS.
Active_comparator: Active control group
Participants in this group will receive active H-coil delivered rTMS.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute on Drug Abuse (NIDA)
Leads: The University of Texas Health Science Center, Houston

This content was sourced from clinicaltrials.gov

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