Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)
Status: Recruiting
Location: See location...
Intervention Type: Device, Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from H coil combined with cognitive training for improving white matter integrity.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:
• Male and female ages between ages 18-60 years
• Ability to give written informed consent (age 18 or above)
• Diagnosed with schizophrenia-spectrum disorder and Evaluation to Sign Consent (ESC) above 10.
Locations
United States
Texas
The University of Texas Health Science Center, Houston
RECRUITING
Houston
Contact Information
Primary
Bhim M Adhikari
bhim.m.adhikari@uth.tmc.edu
713-486-2740
Backup
Xiaoming Du, PhD
Xiaoming.Du@uth.tmc.edu
443-882-9717
Time Frame
Start Date: 2025-06-03
Estimated Completion Date: 2029-05-01
Participants
Target number of participants: 120
Treatments
Experimental: Active rTMS combined with Cognitive Training
Participants will receive active H-coil delivered rTMS, as well as cognitive training in each treatment visit for up to 10 treatment visits within about 2 weeks. In each visit, there are three rTMS sessions and each of them is followed by a cognitive training session and a rest period, which allows the inter-rTMS-session interval to be about 30 minutes.
Related Therapeutic Areas
Sponsors
Leads: The University of Texas Health Science Center, Houston