Real-time fMRI Neurofeedback as a Tool to Mitigate Auditory Hallucinations in Patients With Schizophrenia - R33 Phase
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication resistant AH.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 55
Healthy Volunteers: f
View:
• patients diagnosed with SZ or schizoaffective disorder using DSM-5 criteria
• auditory hallucinations not responsive to pharmacology as determined by chart review and a clinical interview of SCID.
Locations
United States
Massachusetts
Boston VA Healthcare System, Brockton
RECRUITING
Brockton
Contact Information
Primary
margaret niznikiewicz, PhD
margaret_niznikiewicz@hms.harvard.edu
6176534627
Backup
Clemens Bauer, phd
c.bauer@northeastern.edu
617-870-1771
Time Frame
Start Date: 2022-03-01
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 104
Treatments
Experimental: stg-rt-fMRI
will receive feedback from the STG
Sham_comparator: sham-rt-fMRI
will receive feedback from the motor cortex
Related Therapeutic Areas
Sponsors
Collaborators: Cambridge Health Alliance, Northeastern University, Mclean Hospital
Leads: Boston VA Research Institute, Inc.