Empirical Validation of a Cerebellar-cortical Hallucination Circuit
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study how hallucinations work in schizophrenia. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study the investigators will be stimulating the brain to learn more about how TMS might improve these symptoms of schizophrenia.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 55
Healthy Volunteers: f
View:
• Diagnosis of schizophrenia or schizoaffective disorder
Locations
United States
Massachusetts
McLean Hospital
RECRUITING
Belmont
Contact Information
Primary
Mark Halko, PhD
mhalko@mclean.harvard.edu
Time Frame
Start Date: 2021-10-13
Estimated Completion Date: 2026-10-31
Participants
Target number of participants: 68
Treatments
Active_comparator: Active cerebellum rTMS
Cerebellar targeted iTBS, twice daily, one week.
Sham_comparator: Sham cerebellum rTMS
Cerebellar targeted sham iTBS, twice daily, one week.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute of Mental Health (NIMH), Beth Israel Deaconess Medical Center
Leads: Mclean Hospital